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1.5.3.14: polyamine oxidase (propane-1,3-diamine-forming)

This is an abbreviated version!
For detailed information about polyamine oxidase (propane-1,3-diamine-forming), go to the full flat file.

Word Map on EC 1.5.3.14

Reaction

spermidine
+
O2
 +
H2O
=
propane-1,3-diamine
 +
4-aminobutanal
 +
H2O2

Synonyms

EC 1.5.3.11, flavin-containing polyamine oxidase, maize PAO, maize polyamine oxidase, MPAO, OsPAO7, PAO, ZmPAO

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.3 With oxygen as acceptor
                1.5.3.14 polyamine oxidase (propane-1,3-diamine-forming)

Inhibitors

Inhibitors on EC 1.5.3.14 - polyamine oxidase (propane-1,3-diamine-forming)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(N1-5-aminopentyl)-N3-(cyclohexylethyl)-N1,N2,N3-tris(tert-butoxycarbonyl)guanidine
-
1,10-Diaminodecane
-
1,12-diaminododecane
-
1,19-bis(ethylamino)-5,10,15-triazanonadecane
-
i.,e. SL-11061, 68% inhibition at 0.5 mM
1,3-diaminopropane
-
1,4-diaminobutane
-
1,5-Diaminopentane
-
1,6-diaminohexane
-
1,7-Diaminoheptane
-
1,8-diaminooctane
1,9-diaminononane
-
1-(4-aminobutyl)-3-(4-fluorobenzyl)guanidine
1-(4-aminobutyl)-3-but-3-en-1-ylguanidine
competitive inhibition of spermidine oxidation
1-(4-aminobutyl)-3-but-3-yn-1-ylguanidine
competitive inhibition of spermidine oxidation
1-(4-aminobutyl)-3-prop-2-en-1-ylguanidine
-
1-(4-aminobutyl)-3-prop-2-yn-1-ylguanidine
-
1-(4-carbamimidamidobutyl)-3-(3-methylbut-2-en-1-yl)guanidine
-
1-(5-aminopentyl)-3-(2-cyclohexylethyl)guanidine
-
1-(5-aminopentyl)-3-(2-cyclopropylethyl)guanidine
-
1-(5-aminopentyl)-3-(3-methoxybenzyl)guanidine
-
1-(5-aminopentyl)-3-(3-methylbut-2-en-1-yl)guanidine
-
1-(5-aminopentyl)-3-(4-methylpent-3-en-1-yl)guanidine
competitive inhibition of spermidine oxidation
1-(5-aminopentyl)-3-[(2E)-3-phenylprop-2-en-1-yl]guanidine
-
1-(6-aminohexyl)-3-(3-methylbut-2-en-1-yl)guanidine
-
1-(6-aminohexyl)-3-(4-methylpent-3-en-1-yl)guanidine
competitive inhibition of spermidine oxidation
1-(guanidino)-17-(N1-(gamma,gamma-dimethylallyl)guanidino)-9-azaheptadecane tris(trifluoroacetate)
-
1-[3-[(3-aminopropyl)amino]propyl]-3-(3-methylbut-2-en-1-yl)guanidine
-
1-[7-[(9-carbamimidamidononyl)amino]heptyl]-3-(2-cyclopropylethyl)guanidine
-
1-[7-[(9-carbamimidamidononyl)amino]heptyl]-3-(2-phenylethyl)guanidine
-
1-[7-[(9-carbamimidamidononyl)amino]heptyl]-3-(3-methylbut-3-en-1-yl)guanidine
-
3-(4-methylpent-3-en-1-yl)-1-[9-([7-[(4-methylpent-3-en-1-yl)carbamimidamido]heptyl]amino)nonyl]guanidine
-
3-but-3-yn-1-yl-1-[7-[(9-carbamimidamidononyl)amino]heptyl]guanidine
-
3-[(2E)-but-2-en-1-yl]-1-[7-[(9-carbamimidamidononyl)amino]heptyl]guanidine
-
agmatine
DELTA1-pyrroline
competitive
diazabicyclononane
competitive
diphenylene iodonium
-
slight inhibition of PAO
guazatine
iminoctadine
-
N,N'''-butane-1,4-diylbis[3-(3-methylbut-2-en-1-yl)guanidine]
N,N'-bis(2,3-butadienyl)-1,4-butane-diamine
i.e. MDL72527
N,N'-diaminoguanidine
-
about 25% inmhibition at 0.5 mM
N-prenyl agmatine
-
N-prenylagmatine
-
i.e. G3, a specific and selective ZmPAO inhibitor. G3 strongly inhibits lignin and suberin polyphenolic domain deposition along the wound periderm in maize mesocoty
N1,N2-bis(tert-butoxycarbonyl)-N1-(cyclohexylethyl)-S-methylisothiourea
-
N1,N2-bis(tert-butoxycarbonyl)-N1-(gamma,gamma-dimethylallyl)-S-methylisothiourea
-
N1,N2-bis(tert-butoxycarbonyl)-N1-(gamma,gamma-methylallyl)-S-methylisothiourea
-
N1-(3-methoxybenzyl)-N3-(5-aminopentyl)-N2,N3,N4-tris(tertbutoxycarbonyl)guanidine
-
N1-acetyl-3-aminopropyl-4-aminobutanal
competitive
N1-acetylspermine
N1-benzylamine-N3-(gamma,gamma-dimethyallyl)-N2,N3,N4-tris(tert-butoxycarbonyl)guanidine
-
N1-benzylamine-N3-(gamma,gamma-dimethylallyl)guanidine bis-(trifluoroacetate)
-
N1-[(30-aminopropyl)-3-aminopropyl]-N3-(gamma,gamma-dimethylallyl)-N2,N3-bis(tert-butoxycarbonyl)guanidine
-
prenylagmatine
-
SL-11061
-
i.e. 1,19-bis-(ethylamine)-5,10,15 triazanonadecane
tert-butyl (2E)-but-2-en-1-yl[(E)-[(tert-butoxycarbonyl)imino](methylsulfanyl)methyl]carbamate
-
tert-butyl (4-[(tert-butoxycarbonyl)[(E)-[(tert-butoxycarbonyl)imino](methylsulfanyl)methyl]amino]butyl)methylcarbamate
-
tert-butyl (6-aminohexyl)[(tert-butoxycarbonyl)(cyclopropylmethyl)carbamimidoyl]carbamate
-
tert-butyl (6-aminohexyl)[(tert-butoxycarbonyl)[(3E)-4-phenylbut-3-en-1-yl]carbamimidoyl]carbamate
-
tert-butyl benzyl[(E)-[(tert-butoxycarbonyl)imino](methylsulfanyl)methyl]carbamate
-
tert-butyl [(1E)-[(tert-butoxycarbonyl)(cyclopropylmethyl)amino](methylsulfanyl)methylidene]carbamate
-
tert-butyl [(E)-[(tert-butoxycarbonyl)imino](methylsulfanyl)methyl]prop-2-yn-1-ylcarbamate
-
tert-butyl [(E)-[(tert-butoxycarbonyl)imino](methylsulfanyl)methyl][(2E)-3-phenylprop-2-en-1-yl]carbamate
-
additional information
-