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1.5.1.B5: DELTA1-piperideine-2-carboxylate/DELTA1-pyrroline-2-carboxylate reductase (NADH)

This is an abbreviated version!
For detailed information about DELTA1-piperideine-2-carboxylate/DELTA1-pyrroline-2-carboxylate reductase (NADH), go to the full flat file.

Word Map on EC 1.5.1.B5

Reaction

L-pipecolate
+
NAD+
=
DELTA1-piperideine-2-carboxylate
+
NADH
+
H+

Synonyms

DELTA-pyrroline-2-carboxylate reductase, DELTA1-pyrroline-2-carboxylate reductase, NADH-dependent Pyr2C reductase, Pyr2C reductase, TlLhpI, tlPyr2C

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.B5 DELTA1-piperideine-2-carboxylate/DELTA1-pyrroline-2-carboxylate reductase (NADH)

pH Optimum

pH Optimum on EC 1.5.1.B5 - DELTA1-piperideine-2-carboxylate/DELTA1-pyrroline-2-carboxylate reductase (NADH)

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
11
H3ZMH3; H3ZMH4
substrates: L-proline + NAD+
11.5
-
L-proline oxidation
4 - 6
H3ZMH3; H3ZMH4
substrates: DELTA1-pyrroline-2-carboxylate + NADH + H+
6 - 10
-
broad optimum of wild-type enzyme and mutant N168A
6.5
-
1-pyrroline-2-carboxylate reduction
7
-
optimum of mutant R43A