1.5.1.49: 1-pyrroline-2-carboxylate reductase [NAD(P)H]
This is an abbreviated version!
For detailed information about 1-pyrroline-2-carboxylate reductase [NAD(P)H], go to the full flat file.
Reaction
Synonyms
LhpH
ECTree
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Cofactor
Cofactor on EC 1.5.1.49 - 1-pyrroline-2-carboxylate reductase [NAD(P)H]
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NAD+
in the oxidization of L-proline the ratio of NADP+ to NAD+ in kcat/Km value is about 150:1
NADH
the preferred cofactor is NADPH, lower activity with NADH. The kcat/Km value for DELTA1-pyrroline-2-carboxylate in the presence of NADH is 5.6fold lower than that in the presence of NADPH, mainly caused by the 12fold lower kcat value
NADP+
in the oxidization of L-proline the ratio of NADP+ to NAD+ in kcat/Km value is about 150:1
NADPH
the preferred cofactor is NADPH, lower activity with NADH. The kcat/Km value for DELTA1-pyrroline-2-carboxylate in the presence of NADH is 5.6fold lower than that in the presence of NADPH, mainly caused by the 12fold lower kcat value