1.5.1.43: carboxynorspermidine synthase

This is an abbreviated version!
For detailed information about carboxynorspermidine synthase, go to the full flat file.

Reaction

Synonyms

ASA-DAP Schiff base reductase, Atu4170, C-NSPD synthase, CANSDH, carboxy(nor)spermidine dehydrogenase, carboxynorspermidine dehydrogenase, carboxynorspermidine synthase, carboxyspermidine dehydrogenase, CASDH, VC1624

ECTree

     1 Oxidoreductases

         1.5 Acting on the CH-NH group of donors

             1.5.1 With NAD⁺ or NADP⁺ as acceptor

                1.5.1.43 carboxynorspermidine synthase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
2	Activating Compound
396	AA Sequence
2	Cloned(Commentary)
5	Cofactor
2	Expression
13	General Information
3	Inhibitors
2	KM Value [mM]
1	Metals/Ions
2	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
12	Organism
6	Pathway
1	pH Optimum
1	pH Range
1	pH Stability
1	pI Value
1	Protein Variants
1	Purification (Commentary)
2	Reaction
10	Reference
2	Specific Activity [micromol/min/mg]
1	Storage Stability
22	Substrates and Products (Substrate)
2	Subunits
32	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]

Systematic Name

print visible entries

print all entries

Systematic Name on EC 1.5.1.43 - carboxynorspermidine synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Systematic Name Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SYSTEMATIC NAME

IUBMB Comments

carboxynorspermidine:NADP+ oxidoreductase

The reaction takes place in the opposite direction. Part of a bacterial polyamine biosynthesis pathway. L-aspartate 4-semialdehyde and propane-1,3-diamine/putrescine form a Schiff base that is reduced to form carboxynorspermidine/carboxyspermidine, respectively [1]. The enzyme from the bacterium Vibrio cholerae is essential for biofilm formation [2]. The enzyme from Campylobacter jejuni only produces carboxyspermidine in vivo even though it also can produce carboxynorspermidine in vitro [3].