1.5.1.3: dihydrofolate reductase

This is an abbreviated version!
For detailed information about dihydrofolate reductase, go to the full flat file.

Reaction

Synonyms

5,6,7,8-tetrahydrofolate: NADP+ oxidoreductase, 7,8-dihydrofolate reductase, At2g16370, At4g34570, bifunctional dihydrofolate reductase-thymidylate synthase, bifunctional TS-DHFR, BmDHFR, dehydrogenase, tetrahydrofolate, DFR-TS, DFR1, DfrA, DfrB, DHFR, DHFR type IIIC, DHFR-TS, DHFR-TS1, DHFR-TS2, DHFR2, DHFRL1, DHFRLS, dihydrofolate reductase, dihydrofolate reductase-like, dihydrofolate reductase-thymidylate synthase, dihydrofolate reductase:thymidylate synthase, dihydrofolic acid reductase, dihydrofolic reductase, EC 1.5.1.4, ecDHFR, folA, folA3, folic acid reductase, folic reductase, FolM, hDHFR, hDHFR-1, hDHFR-2, HjDHFR, hvDHFR1, hvDHFR2, LAU_0427, LBRM_06_0830, mDHFR, mjDHFR, More, myDHFR, NADPH-dihydrofolate reductase, pcDHFR, PKNH_0509600, ppDHFR, pteridine reductase, pteridine reductase:dihydrofolate reductase, PTR2, R-plasmid-encoded dihydrofolate reductase, R67 DHFR, R67 dihydrofolate reductase, reductase, dihydrofolate, S3DHFR, Smdhfr, Smp 175230, spDHFR, svDHFR, tcptr1, tetrahydrofolate dehydrogenase, THY-1, THY-2, thymidylate synthase-dihydrofolate reductase, thymidylate synthetase-dihydrofolate reductase, Trimethoprim resistance protein, TS-DHFR, WUBG_00817

ECTree

     1 Oxidoreductases

         1.5 Acting on the CH-NH group of donors

             1.5.1 With NAD⁺ or NADP⁺ as acceptor

                1.5.1.3 dihydrofolate reductase

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All data fields related to EC 1.5.1.3

Results	in table
44	Activating Compound
38742	AA Sequence
88	Application
1	CAS Registry Number
101	Cloned(Commentary)
250	Cofactor
77	Crystallization (Commentary)
5136	Disease/ Diagnostics
2	Expression
68	General Information
36	General Stability
747	IC50 Value
1679	Inhibitors
89	kcat/KM [mM/s]
479	Ki Value [mM]
513	KM Value [mM]
18	Localization
28	Metals/Ions
105	Molecular Weight [Da]
103	Natural Substrates/ Products (Substrates)
4	Organic Solvent Stability
865	Organism
9	Pathway
805	PDB ID
155	pH Optimum
22	pH Range
3	pH Stability
1	pI Value
1	Posttranslational Modification
264	Protein Variants
149	Purification (Commentary)
47	Reaction
4	Reaction Type
460	Reference
13	Renatured (Commentary)
95	Source Tissue
131	Specific Activity [micromol/min/mg]
26	Storage Stability
363	Substrates and Products (Substrate)
101	Subunits
232	Synonyms
1	Systematic Name
88	Temperature Optimum [°C]
1	Temperature Range [°C]
53	Temperature Stability [°C]
295	Turnover Number [1/s]