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1.5.1.28: Opine dehydrogenase

This is an abbreviated version!
For detailed information about Opine dehydrogenase, go to the full flat file.

Word Map on EC 1.5.1.28

Reaction

(2S)-2-{[1-(R)-Carboxyethyl]amino}pentanoate
+
NAD+
 +
H2O
=
L-2-aminopentanoic acid
 +
pyruvate
 +
NADH
 +
H+

Synonyms

Dehydrogenase, opine, N-(1-D-Carboxyethyl)-L-norvaline dehydrogenase, N-[1-(R)-(Carboxy)ethyl]-(S)-norvaline: NAD+ oxidoreductase (L-norvaline forming), ODH, OpDH

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.28 Opine dehydrogenase

KM Value

KM Value on EC 1.5.1.28 - Opine dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
11.9
(R,S)-2,3-diaminopropionic acid
-
pyruvate and NADH as cosubstrates
20
(S)-2-aminobutanoate
-
pyruvate and NADH as cosubstrates
3.72
(S)-norleucine
-
pyruvate and NADH as cosubstrates
2.17
(S)-norvaline
-
pyruvate and NADH as cosubstrates
28
2-Oxohexanoate
-
L-Met and NADH as cosubstrate
3.19
beta-chloro-(S)-alanine
-
pyruvate and NADH as cosubstrates
8.8
glyoxylate
-
L-Met and NADH as cosubstrate
5.1
L-Ala
-
pyruvate and NADH as cosubstrates
2.5
L-Cys
-
pyruvate and NADH as cosubstrates
6.2
L-Ile
-
pyruvate and NADH as cosubstrates
2.9
L-Leu
4.1
L-Met
-
pyruvate and NADH as cosubstrates
7.5 - 8.7
L-Phe
28.3
L-phenylglycine
-
pyruvate and NADH as cosubstrates
3.6
L-Ser
-
pyruvate and NADH as cosubstrates
7.4
L-Thr
-
pyruvate and NADH as cosubstrates
3
L-Val
-
pyruvate and NADH as cosubstrates
5.94
O-acetyl-(S)-Ser
-
pyruvate and NADH as cosubstrates
8.7
O-phospho-(S)-Ser
-
pyruvate and NADH as cosubstrates
3.5
oxaloacetate
-
L-Met and NADH as cosubstrate
3
pyruvate
-
L-Met and NADH as cosubstrate