Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.5.1.18: ephedrine dehydrogenase

This is an abbreviated version!
For detailed information about ephedrine dehydrogenase, go to the full flat file.

Reaction

(-)-ephedrine
+
NAD+
=
(R)-2-Methylimino-1-phenylpropan-1-ol
+
NADH
+
H+

Synonyms

EDH

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.18 ephedrine dehydrogenase

Application

Application on EC 1.5.1.18 - ephedrine dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
synthesis
the wide substrate spectrum of the dehydrogenase, combined with its regio- and enantioselectivity, suggests a high potential for the industrial production of valuable chiral compounds
additional information
both (R,S)-(-)-ephedrine and (S,S)-(+)-pseudoephedrine are constituents of various over-the-counter (OTC) drugs and are also used as decongestants and stimulants. Arthrobacter sp. TS-15 and its isolated ephedrine-oxidizing enzymes have potential for use in decontamination and synthetic applications