1.5.1.17: alanopine dehydrogenase
This is an abbreviated version!
For detailed information about alanopine dehydrogenase, go to the full flat file.
Word Map on EC 1.5.1.17
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1.5.1.17
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analysis
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fulgidus
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1.4.1.1
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archaeoglobus
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proteolyticus
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cyclodeaminase
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phormidium
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octopine
-
diagnostics
- 1.5.1.17
- analysis
- fulgidus
-
1.4.1.1
- archaeoglobus
- proteolyticus
-
cyclodeaminase
-
phormidium
- octopine
- diagnostics
Reaction
Synonyms
ADH, ALADH, AlaDHAm, ALPDH, Dehydrogenase, alanopine, meso-N-(1-Carboxyethyl)-alanine dehydrogenase
ECTree
1.5.1.17 alanopine dehydrogenaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 1.5.1.17 - alanopine dehydrogenase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2,2'-iminodipropanoate + NAD+ + H2O
L-alanine + pyruvate + NADH + H+
-
-
-
-
r
glycine + pyruvate + NADH + H+
? + NAD+ + H2O
reductive condensation, low activity
-
-
?
Gly + pyruvate + NADH
Strombine + NAD+ + H2O
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at 161.5% of the activity with L-Ala
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?
Gly + pyruvate + NADH
Strombine + NAD+ + H2O
-
at 69% of the activity with L-Ala
-
-
?
Gly + pyruvate + NADH
Strombine + NAD+ + H2O
-
at 9% of the activity with L-Ala
-
-
?
L-2-Aminobutyrate + pyruvate + NADH
?
-
at 60% of the activity with L-Ala
-
-
?
L-2-Aminobutyrate + pyruvate + NADH
?
-
at 94% of the activity with L-Ala
-
-
?
L-Ala + 2-oxobutanoate + NADH
?
-
at 21% of the activity with pyruvate
-
-
?
L-Ala + 2-oxobutanoate + NADH
?
-
at 68% of the activity with pyruvate
-
-
?
L-Ala + 2-oxobutanoate + NADH
?
-
at 22% the activity with pyruvate
-
-
?
L-Ala + 2-oxopentanoate + NADH
?
-
at 25.6% of the activity with pyruvate
-
-
?
L-Ala + 2-oxopentanoate + NADH
?
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at 58% of the activity with pyruvate
-
-
?
L-Ala + hydroxypyruvate + NADH
?
-
at 12.8% of the activity with pyruvate
-
-
?
L-Ala + hydroxypyruvate + NADH
?
-
at 3.3% of the activity with pyruvate
-
-
?
L-Ala + oxaloacetate + NADH
?
-
at 106.6% of the activity with pyruvate
-
-
?
L-Ala + pyruvate + NADH
2,2'-Iminodipropanoate + NAD+ + H2O
Busycotypus canaliculatum
-
-
-
-
?
L-Ala + pyruvate + NADH
2,2'-Iminodipropanoate + NAD+ + H2O
-
-
-
-
?
L-alanine + pyruvate + NADH + H+
2,2'-iminodipropanoate + NAD+ + H2O
reductive condensation, the enzyme is highy specific for L-alanine
-
-
?
L-alanine + pyruvate + NADH + H+
2,2'-iminodipropanoate + NAD+ + H2O
-
-
-
-
r
additional information
?
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L-alanine binding region of alanopine dehydrogenase near a distinct helix-link-helix motif predicted by unbiased molecular dynamics simulations of ligand diffusion using a homology model of alanopine dehydrogenase, overview
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-
?
additional information
?
-
-
L-alanine binding region of alanopine dehydrogenase near a distinct helix-link-helix motif predicted by unbiased molecular dynamics simulations of ligand diffusion using a homology model of alanopine dehydrogenase, overview
-
-
?
additional information
?
-
Busycotypus canaliculatum
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the enzyme from hepatopancreas is involved in alanopine oxidation
-
-
?
additional information
?
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Busycotypus canaliculatum
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muscle enzyme is involved in anaerobic glycolysis
-
-
?
additional information
?
-
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enzyme catalyzes the terminal step of anaerobic glycolysis during muscle anoxia associated with locomotion
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-
?
additional information
?
-
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the enzyme probably functions in the maintenance of a redox balance during anaerobiosis in the adductor muscle and heart of the oyster
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-
?
additional information
?
-
-
the enzyme functions in cytoplasmic redox balance during anoxia stress
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-
?
additional information
?
-
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the enzyme functions as the terminal dehydrogenase of glycolysis and has a role in maintaining energy production under the stresses of environmental or functional anoxia
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-
?
