1.4.99.6: D-arginine dehydrogenase

This is an abbreviated version!
For detailed information about D-arginine dehydrogenase, go to the full flat file.

Reaction

Synonyms

D-alanine dehydrogenase, D-amino acid dehydrogenase, D-amino acid dehydrogenase DadA, DAADH, DAD, DadA, DADH, DauA, EC 1.4.99.1, NADP+-dependent D-amino acid dehydrogenase

ECTree

     1 Oxidoreductases

         1.4 Acting on the CH-NH₂ group of donors

             1.4.99 With unknown physiological acceptors

                1.4.99.6 D-arginine dehydrogenase

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Results	in table
1	Activating Compound
2290	AA Sequence
1	CAS Registry Number
9	Cloned(Commentary)
9	Cofactor
3	Crystallization (Commentary)
2	Expression
8	General Information
1	General Stability
14	Inhibitors
56	kcat/KM [mM/s]
2	Ki Value [mM]
45	KM Value [mM]
1	Localization
1	Metals/Ions
3	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
26	Organism
2	Pathway
3	PDB ID
6	pH Optimum
9	Protein Variants
5	Purification (Commentary)
5	Reaction
4	Reaction Type
24	Reference
2	Source Tissue
16	Specific Activity [micromol/min/mg]
114	Substrates and Products (Substrate)
4	Subunits
27	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
44	Turnover Number [1/s]

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TURNOVER NUMBER [1/s]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

5700

2-oxo-4-methylvaleric acid

Ureibacillus thermosphaericus

-

at pH 10.5 and 50°C

724092

0.74

D-alanine

Pseudomonas aeruginosa

Q9HTQ0

pH 8.7, 37°C

748083

1.27 - 420

D-arginine

12 entries

0.84 - 35

D-histidine

5 entries

0.061 - 55

D-leucine

4 entries

9.2 - 550

D-Lysine

4 entries

6.8 - 190

D-methionine

4 entries

6.2

D-ornithine

Pseudomonas aeruginosa

-

-

705583

1.1 - 75

D-phenylalanine

4 entries

0.97

D-proline

Pseudomonas aeruginosa

Q9HTQ0

pH 8.7, 37°C

748083

0.8

D-serine

Pseudomonas aeruginosa

Q9HTQ0

pH 8.7, 37°C

748083

0.68

D-threonine

Pseudomonas aeruginosa

Q9HTQ0

pH 8.7, 37°C

748083

1.1 - 23

D-tyrosine

4 entries

0.78

D-valine

Pseudomonas aeruginosa

Q9HTQ0

pH 8.7, 37°C

748083

1.27

D-arginine

Pseudomonas aeruginosa

Q9HTQ0

pH 8.7, 37°C

748083

1.4

D-arginine

Pseudomonas aeruginosa

Q9HXE3

mutant S45A, pH 5.5, 25°C

740089

11.1

D-arginine

Pseudomonas aeruginosa

-

-

705583

23

D-arginine

Pseudomonas aeruginosa

Q9HXE3

mutant A46G, pH 6.5, 25°C

740089

160

D-arginine

Pseudomonas aeruginosa

Q9HXE3

wild-type, pH-independent limiting value at high pH, pH not specified in the publication, temperature not specified in the publication

733215

204

D-arginine

Pseudomonas aeruginosa

Q9HXE3

pH 8.7, 25°C

733326, 733327

204

D-arginine

Pseudomonas aeruginosa

-

pH 8.7, 25°C

733327

204

D-arginine

Pseudomonas aeruginosa

Q9HXE3

pH 8.7, 25°C

762668

204

D-arginine

Pseudomonas aeruginosa

Q9HXE3

mutant Y249F, pH 8.7, 25°C

733354

210

D-arginine

Pseudomonas aeruginosa

Q9HXE3

mutant A46G, pH 10.0, 25°C

740089

290

D-arginine

Pseudomonas aeruginosa

Q9HXE3

mutant S45A, pH 10.0, 25°C

740089

420

D-arginine

Pseudomonas aeruginosa

Q9HXE3

mutant Y53F, pH 8.7, 25°C

733354

0.84

D-histidine

Pseudomonas aeruginosa

Q9HTQ0

pH 8.7, 37°C

748083

3.6

D-histidine

Pseudomonas aeruginosa

-

-

705583

35

D-histidine

Pseudomonas aeruginosa

Q9HXE3

pH 8.7, 25°C

733326, 733327

35

D-histidine

Pseudomonas aeruginosa

-

pH 8.7, 25°C

733327

35

D-histidine

Pseudomonas aeruginosa

Q9HXE3

pH 8.7, 25°C

762668

0.061

D-leucine

Pseudomonas aeruginosa

Q9HXE3

wild-type, pH 6.0, 25°C

733215

6.4

D-leucine

Pseudomonas aeruginosa

Q9HXE3

pH 8.7, 25°C

733326, 762668

6.4

D-leucine

Pseudomonas aeruginosa

-

pH 8.7, 25°C

762668

55

D-leucine

Pseudomonas aeruginosa

Q9HXE3

wild-type, pH 10.0, 25°C

733215

9.2

D-Lysine

Pseudomonas aeruginosa

-

-

705583

141

D-Lysine

Pseudomonas aeruginosa

Q9HXE3

pH 8.7, 25°C

733326, 762668

141

D-Lysine

Pseudomonas aeruginosa

-

pH 8.7, 25°C

762668

550

D-Lysine

Pseudomonas aeruginosa

Q9HXE3

wild-type, pH-independent limiting value at high pH, pH not specified in the publication, temperature not specified in the publication

733215

6.8

D-methionine

Pseudomonas aeruginosa

-

-

705583

154

D-methionine

Pseudomonas aeruginosa

Q9HXE3

pH 8.7, 25°C

733326, 762668

154

D-methionine

Pseudomonas aeruginosa

-

pH 8.7, 25°C

762668

190

D-methionine

Pseudomonas aeruginosa

Q9HXE3

wild-type, pH-independent limiting value at high pH, pH not specified in the publication, temperature not specified in the publication

733215

1.1

D-phenylalanine

Pseudomonas aeruginosa

Q9HTQ0

pH 8.7, 37°C

748083

5.3

D-phenylalanine

Pseudomonas aeruginosa

-

-

705583

75

D-phenylalanine

Pseudomonas aeruginosa

Q9HXE3

pH 8.7, 25°C

733326, 762668

75

D-phenylalanine

Pseudomonas aeruginosa

-

pH 8.7, 25°C

762668

1.1

D-tyrosine

Pseudomonas aeruginosa

Q9HTQ0

pH 8.7, 37°C

748083

3.6

D-tyrosine

Pseudomonas aeruginosa

-

-

705583

23

D-tyrosine

Pseudomonas aeruginosa

Q9HXE3

pH 8.7, 25°C

733326, 762668

23

D-tyrosine

Pseudomonas aeruginosa

-

pH 8.7, 25°C

762668