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1.4.99.2: taurine dehydrogenase

This is an abbreviated version!
For detailed information about taurine dehydrogenase, go to the full flat file.

Word Map on EC 1.4.99.2

Reaction

taurine
+
H2O
+
acceptor
=
2-sulfoacetaldehyde
+
NH3
+
reduced acceptor

Synonyms

taurine dehydrogenase, TauXY, TauY, TDH

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.99 With unknown physiological acceptors
                1.4.99.2 taurine dehydrogenase

General Information

General Information on EC 1.4.99.2 - taurine dehydrogenase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
-
individual deletion mutants of tauR, tauC, and tauY, show growth defects. Growth is restored when each mutant is complemented with the appropriate gene on a plasmid, suggesting that the individual deletions do not deter expression of downstream genes, they are not polar mutations. Induced or uninduced DELTAtauY mutant displays the highest levels of reporter expression compared to other strains grown under similar conditions. Increased accumulation of taurine, and thus enhanced expression, occurs in the DELTAtauY mutant due to its inability to degrade the sulfonate compound
physiological function
-
the genes of the tau region, tauR, tauC, and tauY, are each required for taurine dissimilation in Sinorhizobium meliloti. Enzyme TauY is involved in the degradation of taurine, most likely by forming part of the taurine dehydrogenase