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1.4.3.5: pyridoxal 5'-phosphate synthase

This is an abbreviated version!
For detailed information about pyridoxal 5'-phosphate synthase, go to the full flat file.

Word Map on EC 1.4.3.5

Reaction

pyridoxamine 5'-phosphate
+
H2O
 +
O2
=
pyridoxal 5'-phosphate
 +
NH3
 +
H2O2

Synonyms

ePNPOx, FprA protein, oxidase, pyridoxamine phosphate, Pdx1, PDX3, PdxH, PMP oxidase, PNP oxidase, PNP/PMP oxidase, PNPO, PNPOx, PPOX, pyridox(am)ine 5'-phosphate oxidase, pyridoxal 5'-phosphate synthase, pyridoxal 5'-phosphate synthetic enzyme, pyridoxamine (pyridoxine) 5'-phosphate oxidase, pyridoxamine (pyridoxine) 5’-phosphate:O2 oxidoreductase (deaminating), pyridoxamine 5'-phosphate oxidase, pyridoxamine phosphate oxidase, pyridoxamine-5-phosphate oxidase, pyridoxamine-phosphate oxidase, pyridoxaminephosphate oxidase (EC 1.4.3.5: deaminating), pyridoxinamine 5'-phosphate oxidase, pyridoxine (pyridoxamine) 5 '-phosphate oxidase, pyridoxine (pyridoxamine) 5'-phosphate oxidase, pyridoxine (pyridoxamine) phosphate oxidase, pyridoxine 5'-phosphate oxidase, pyridoxine 5'-phosphate oxidase`, pyridoxine 5-phosphate oxidase, pyridoxine phosphate oxidase, pyridoxine-5'-phosphate oxidase, pyridoxine/pyridoxamine 5'-phosphate oxidase, pyridoxine/pyridoxamine phosphate oxidase, sgll, Sgll/PNPO, Ylr456w, Ypr172w

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.5 pyridoxal 5'-phosphate synthase

Cloned

Cloned on EC 1.4.3.5 - pyridoxal 5'-phosphate synthase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli
-
expressed in Escherichia coli BL21 DE3 Rosetta cells
-
expressed in Escherichia coli BL21(DE3) cells
expression in Escherichia coli
expression in Escherichia coli as maltose binding protein fusion
-
expression in Escherichia coli MDS00 strain cells lacking pdxH gene
-
expression of GST-tagged wild-type and of GST-tagged selenomethionine-labeled enzymes from strain Rv2074 in Escherichia coli strain BL21(DE3)
-
expression of mutant enzyme R118Q in Escherichia coli
expression of the GST-tagged enzyme from strain Rv1155 in Escherichia coli strain BL21(DE3)
gene AT5g49970, DNA and amino acid sequence determination and analysis, functional expression with and without N-terminal chloroplast transit peptide in Escherichia coli, functional complementation of a oxidation-sensitive Saccharomyces cerevisiae PDX3 knockout mutant
-
gene PNPO, DNA and amino acid sequence determination and analysis, expression of wild-type PNPO and mutant R229W in CHO cells
-
PNPO gene, DNA and amino acid sequence determination and analysis, genomic organization, expression in Escherichia coli strain BL21 (DE3)
several pyridoxamine 5'-phosphate oxidase pathogenic variants responsible for pyridoxamine 5'-phosphate oxidase deficiency (G118R, R141C, R225H, R116Q/R225H, and X262Q) are recombinantly expressed in Escherichia coli
wild-type and mutant enzyme