Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.4.3.5: pyridoxal 5'-phosphate synthase

This is an abbreviated version!
For detailed information about pyridoxal 5'-phosphate synthase, go to the full flat file.

Word Map on EC 1.4.3.5

Reaction

pyridoxamine 5'-phosphate
+
H2O
 +
O2
=
pyridoxal 5'-phosphate
 +
NH3
 +
H2O2

Synonyms

ePNPOx, FprA protein, oxidase, pyridoxamine phosphate, Pdx1, PDX3, PdxH, PMP oxidase, PNP oxidase, PNP/PMP oxidase, PNPO, PNPOx, PPOX, pyridox(am)ine 5'-phosphate oxidase, pyridoxal 5'-phosphate synthase, pyridoxal 5'-phosphate synthetic enzyme, pyridoxamine (pyridoxine) 5'-phosphate oxidase, pyridoxamine (pyridoxine) 5’-phosphate:O2 oxidoreductase (deaminating), pyridoxamine 5'-phosphate oxidase, pyridoxamine phosphate oxidase, pyridoxamine-5-phosphate oxidase, pyridoxamine-phosphate oxidase, pyridoxaminephosphate oxidase (EC 1.4.3.5: deaminating), pyridoxinamine 5'-phosphate oxidase, pyridoxine (pyridoxamine) 5 '-phosphate oxidase, pyridoxine (pyridoxamine) 5'-phosphate oxidase, pyridoxine (pyridoxamine) phosphate oxidase, pyridoxine 5'-phosphate oxidase, pyridoxine 5'-phosphate oxidase`, pyridoxine 5-phosphate oxidase, pyridoxine phosphate oxidase, pyridoxine-5'-phosphate oxidase, pyridoxine/pyridoxamine 5'-phosphate oxidase, pyridoxine/pyridoxamine phosphate oxidase, sgll, Sgll/PNPO, Ylr456w, Ypr172w

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.5 pyridoxal 5'-phosphate synthase

Activating Compound

Activating Compound on EC 1.4.3.5 - pyridoxal 5'-phosphate synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-aminobutanoate
-
activation
3-Hydroxyanthranilate
-
145% increase in pyridoxine 5-phosphate oxidase activity, 28% increase in pyridoxamine 5-phosphate oxidase activity
3-hydroxykynurenine
-
125% increase in pyridoxine 5-phosphate oxidase activity, 20% increase in pyridoxamine 5-phosphate oxidase activity
5-hydroxyindolacetate
-
125% increase in pyridoxine 5-phosphate oxidase activity, 9% increase in pyridoxamine 5-phosphate oxidase activity
5-hydroxytryptamine
-
20% increase in pyridoxamine 5-phosphate oxidase activity
alanine
-
activation
ammonium sulfate
-
short incubation activates isozyme E-II, not E-I
cysteine
-
activation
guanidine hydrochloride
-
500 mM, activation at low concentrations and brief periods of exposure, inactivation at higher concentrations and longer periods of exposure
guanidine hydrochloride urea
-
both activates and denatures the enzyme
Tris
-
activation
tryptamine
-
27% increase in pyridoxamine 5-phosphate oxidase activity
valine
-
activation
xanthurenate
-
21% increase in pyridoxine 5-phosphate oxidase activity
additional information
-
the enzyme is induced by light without affecting the substrate specificity
-