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1.4.3.4: monoamine oxidase

This is an abbreviated version!
For detailed information about monoamine oxidase, go to the full flat file.

Word Map on EC 1.4.3.4

Reaction

RCH2NHR'
+
H2O
 +
O2
=
RCHO
 +
R'NH2
 +
H2O2

Synonyms

adrenaline oxidase, amine-oxygen oxidoreductase, C-MAO, EC 1.4.3.9, epinephrine oxidase, MAO, MAO A, MAO B, MAO type B, MAO-A, MAO-B, MAO-N, MAO-N-D5, MAOA, MAOB, monoamine oxidase, monoamine oxidase A, monoamine oxidase B, monoamine oxidase N, monoamine oxidase type B, monoamine oxidase-A, monoamine oxidase-B, monoamine oxidaseA, monoamine oxidases A, monoamine oxidases B, monoamine-oxidase-A, monoamine: O2-oxidoreductase, deaminated, monoamine: O2-oxidoreductase, deaminating, monoamine: O2-oxidoreductase: deaminating, monoamine:O2 oxidoreductase (deaminating), monoamine:O2 oxidoreductase, deaminating, monoamine:O2-oxidoreductase deaminating, monoaminoxidase B, More, semicarbazide-sensitive amine oxidase, serotonin deaminase, SSAO, tyraminase, tyramine oxidase, zMAO

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.4 monoamine oxidase

Expression

Expression on EC 1.4.3.4 - monoamine oxidase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
a knockdown of SRY expression substantially reduces both MAO A 2- and 0.24-kb core-promoter activities to below 40% in the transfected cells, overview. R1, i.e. RAM2/CDCA7L/JPO2, a transcription repressor, downregulates MAO A gene expression by competing with Sp1 for binding to Sp1 sites
enzyme activity increases up to day 3 after germination, thereafter decreasing again
-
microRNA-142 reduces monoamine oxidase A expression and activity in neuronal cells by downregulating SIRT1
-
Ni2+ and Pb2+ induce the expression of MAO in brain after exposure over 24 h, but the expression level is normalized after 72 h, overview
Ni2+ and Pb2+ reduce the expression of MAO in brain after exposure over 24 h and 72 h, overview
stable overexpression of SRY in the BE(2)C cell line results in ibncreased MAO-A mRNA and catalytic activity levels, SRY increases MAO A-promoter activity up to 6fold in a concentration-dependent manner, overview. Sp1 synergistically enhances the SRY binding to and activation of the MAO A promoter by interacting and forming a transcriptional regulatory complex with SRY at the MAO A core promoter in vivo, Sp4 activates the MAO A core promoter as Sp1. Sp3 represses this activation by competing with Sp1 and Sp4