1.4.3.25: L-arginine oxidase
This is an abbreviated version!
For detailed information about L-arginine oxidase, go to the full flat file.
Reaction
Synonyms
aoxA, ArgO, aroD
ECTree
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Substrates Products
Substrates Products on EC 1.4.3.25 - L-arginine oxidase
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REACTION DIAGRAM
additional information
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enzyme catalyzes the oxidative deamination of the basic amino acids: L-arginine, L-lysine, L-ornithine and L-histidine. In the presence of catalase and of any of these amino acids, 0.5 mol O2 is consumed, and 1 mol ammonia is formed for each mol amino acid oxidized
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5-guanidino-2-oxopentanoate + NH3 + H2O2
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L-arginine + H2O + O2
5-guanidino-2-oxopentanoate + NH3 + H2O2
HW613270
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the enzyme catalyzes the oxidative deamination of L-arginine and converts L-arginine to 2-ketoarginine, which is nonenzymatically converted into 4-guanidinobutyric acid when the hydrogen peroxide formed by L-arginine oxidation is not removed
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L-arginine + H2O + O2
5-guanidino-2-oxopentanoate + NH3 + H2O2
HW613270
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the enzyme catalyzes the oxidative deamination of L-arginine and converts L-arginine to 2-ketoarginine, which is nonenzymatically converted into 4-guanidinobutyric acid when the hydrogen peroxide formed by L-arginine oxidation is not removed
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L-arginine + H2O + O2
5-guanidino-2-oxopentanoate + NH3 + H2O2
wild-type L-glutamate oxidase enzyme shows strict substrate specificity for L-glutamate. The R305E mutant variant of L-glutamate oxidase exhibits strict specificity for L-arginine
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L-arginine + H2O + O2
5-guanidino-2-oxopentanoate + NH3 + H2O2
Synechococcus cedorum
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L-arginine + H2O + O2
5-guanidino-2-oxopentanoate + NH3 + H2O2
Synechococcus cedorum PCC 6908
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L-arginine + H2O + O2
5-guanidino-2-oxopentanoate + NH3 + H2O2
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L-arginine + H2O + O2
5-guanidino-2-oxopentanoate + NH3 + H2O2
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L-arginine + H2O + O2
5-guanidino-2-oxopentanoate + NH3 + H2O2
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L-canavanine + H2O + O2
2-oxocanavanine + NH3 + H2O2
HW613270
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2-oxohistidine + NH3 + H2O2
Synechococcus cedorum
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less than 2% of the activity with L-arginine
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L-histidine + H2O + O2
2-oxohistidine + NH3 + H2O2
Synechococcus cedorum PCC 6908
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less than 2% of the activity with L-arginine
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L-histidine + H2O + O2
2-oxohistidine + NH3 + H2O2
less than 2% of the activity with L-arginine
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L-histidine + H2O + O2
2-oxohistidine + NH3 + H2O2
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less than 2% of the activity with L-arginine
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L-histidine + H2O + O2
2-oxohistidine + NH3 + H2O2
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L-homoarginine + H2O + O2
2-oxohomoarginine + NH3 + H2O2
HW613270
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2-oxolysine + NH3 + H2O2
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15% of the activity with L-arginine
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L-lysine + H2O + O2
2-oxolysine + NH3 + H2O2
Synechococcus cedorum
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81% of the activity with L-arginine
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L-lysine + H2O + O2
2-oxolysine + NH3 + H2O2
Synechococcus cedorum PCC 6908
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81% of the activity with L-arginine
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L-lysine + H2O + O2
2-oxolysine + NH3 + H2O2
73% of the activity with L-arginine
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L-lysine + H2O + O2
2-oxolysine + NH3 + H2O2
82% of the activity with L-arginine
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L-lysine + H2O + O2
2-oxolysine + NH3 + H2O2
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82% of the activity with L-arginine
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L-lysine + H2O + O2
2-oxolysine + NH3 + H2O2
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2-oxoornithine + NH3 + H2O2
Synechococcus cedorum
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35% of the activity with L-arginine
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L-ornithine + H2O + O2
2-oxoornithine + NH3 + H2O2
Synechococcus cedorum PCC 6908
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35% of the activity with L-arginine
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L-ornithine + H2O + O2
2-oxoornithine + NH3 + H2O2
28% of the activity with L-arginine
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L-ornithine + H2O + O2
2-oxoornithine + NH3 + H2O2
46% of the activity with L-arginine
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L-ornithine + H2O + O2
2-oxoornithine + NH3 + H2O2
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28% of the activity with L-arginine
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L-ornithine + H2O + O2
2-oxoornithine + NH3 + H2O2
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