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1.4.3.2: L-amino-acid oxidase

This is an abbreviated version!
For detailed information about L-amino-acid oxidase, go to the full flat file.

Word Map on EC 1.4.3.2

Reaction

an L-amino acid
+
H2O
+
O2
=
a 2-oxo carboxylate
+
NH3
+
H2O2

Synonyms

AAD, ACTX-6, ACTX-8, Akbu-LAAO, APIT, apotxin, aromatic L-amino acid oxidase, Balt-LAAO-I, bordonein-L, Bpir-LAOO-1, CC-LPOX, DAA, Dolabellanin, escapin, head kidney and gill, IL4I1, Il4i1 protein, ink toxin 1, Interleukin Four Induced Gene 1 protein, L-AAO, L-AAO/MOG, L-AAO1, L-amino acid oxidase, L-amino acid: O2 oxidoreductase, L-amino acid:O2 oxidoreductase, L-amino acid:O2 oxidoreductase (deaminating), L-aminooxidase, L-Aox, L-phenylalanine oxidase, LAAO, LAAO-1, LAAO-I, LAAO-II, LAAO1, LAAO4, LAAOI, LAAOII, LAO, LAO1, M-LAO, ophio-amino-acid oxidase, Pm1, RoLAAO, sarA, Sebastes schlegeli antibacterial protein, Sebastes schlegelii antibacterial protein, SSAP, TJ-LAO, toxophallin, TSV-LAO

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.2 L-amino-acid oxidase

Natural Substrates Products

Natural Substrates Products on EC 1.4.3.2 - L-amino-acid oxidase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
an L-amino acid + H2O + O2
a 2-oxo-acid + NH3 + H2O2
show the reaction diagram
-
L-amino-acid oxidase catalyzes the oxidative deamination of a number of L-amino acids to their respective imino acids with concomitant hydrolysis to alpha-keto acids, together with the production of ammonia and hydrogen peroxide
-
-
?
bovine serum albumin + H2O + O2
?
show the reaction diagram
-
37% activity compared to L-Lys
-
-
?
casein + H2O + O2
?
show the reaction diagram
-
59% activity compared to L-Lys
-
-
?
DL-asparagine + H2O + O2
2-oxosuccinamic acid + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
DL-leucine + H2O + O2
2-oxo-4-methylpentanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
DL-methionine + H2O + O2
4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
DL-norleucine + H2O + O2
2-oxocaproate + NH3 + H2O2
show the reaction diagram
DL-threonine + H2O + O2
2-oxo-3-hydroxybutanoic acid + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
DL-tryptophan + H2O + O2
3-(1H-indol-3-yl)-2-oxopropanoic acid + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
DL-valine + H2O + O2
2-oxoisovalerate + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
glutathione + H2O + O2
?
show the reaction diagram
-
97% activity compared to L-Lys
-
-
?
Gly + H2O + O2
glyoxylate + NH3 + H2O2
show the reaction diagram
-
17.8% activity compared to L-Lys
-
-
?
L-Ala + H2O + O2
2-oxopropanoate + NH3 + H2O2
show the reaction diagram
-
lowest activity
-
-
?
L-Ala + H2O + O2
2-oxopropanoic acid + NH3 + H2O2
show the reaction diagram
L-amino acid + H2O + O2
2-oxo acid + NH3 + H2O2
show the reaction diagram
L-amino acid + H2O + O2
2-oxocarboxylate + NH3 + H2O2
show the reaction diagram
L-amino acid + H2O + O2
a 2-oxo carboxylate + NH3 + H2O2
show the reaction diagram
L-Arg + H2O + O2
2-oxo-5-guanidinopentanoic acid + NH3 + H2O2
show the reaction diagram
Bacillus carotarum
-
-
-
-
?
L-Arg + H2O + O2
2-oxo-5-guanidinovaleric acid + NH3 + H2O2
show the reaction diagram
L-Arg + H2O + O2
5-guanidino-2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
?
L-arginine + H2O + O2
2-oxo-5-guanidinopentanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Asn + H2O + O2
2-oxosuccinamic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Asp + H2O + O2
oxaloacetate + NH3 + H2O2
show the reaction diagram
L-Cys + H2O + O2
2-oxo-3-mercaptopropanoic acid + NH3 + H2O2
show the reaction diagram
L-Gln + H2O + O2
5-amino-2,5-dioxopentanoic acid + NH3 + H2O2
show the reaction diagram
L-Glu + H2O + O2
2-oxoglutarate + NH3 + H2O2
show the reaction diagram
L-glutamic acid + H2O + O2
2-oxoglutarate + NH3 + H2O2
show the reaction diagram
L-glutamine + H2O + O2
2-oxo-4-carbamoylbutanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-His + H2O + O2
2-oxo-4-imidazolepropionic acid + NH3 + H2O2
show the reaction diagram
L-histidine + H2O + O2
2-oxo-4-imidazolepropionic acid + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
L-Ile + H2O + O2
3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
show the reaction diagram
L-isoleucine + H2O + O2
3-methyl-2-oxopentanoate + NH3 + H2O2
show the reaction diagram
L-Leu + H2O + O2
2-oxo-4-methylvaleric acid + NH3 + H2O2
show the reaction diagram
L-Leu + H2O + O2
4-methyl-2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-leucine + H2O + O2
2-oxo-4-methylpentanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-leucine + H2O + O2
2-oxo-4-methylvaleric acid + NH3 + H2O2
show the reaction diagram
L-leucine + H2O + O2
4-methyl-2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
L-Lys + H2O + O2
6-amino-2-oxo-hexanoic acid + NH3 + H2O2
show the reaction diagram
L-Lys + H2O + O2
6-amino-2-oxohexanoate + NH3 + H2O2
show the reaction diagram
L-Lys + H2O + O2
6-amino-2-oxohexanoic acid + NH3 + H2O2
show the reaction diagram
L-lysine + H2O + O2
6-amino-2-oxohexanoic acid + NH3 + H2O2
show the reaction diagram
L-Met + H2O + O2
4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
L-methionine + H2O + O2
4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
L-Orn + H2O + O2
2-oxo-5-aminopentanoate + NH3 + H2O2
show the reaction diagram
L-Orn + H2O + O2
5-amino-2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
?
L-Phe + H2O + O2
2-oxo-3-phenylpropanoate + NH3 + H2O2
show the reaction diagram
L-Phe + H2O + O2
phenylpyruvate + NH3 + H2O2
show the reaction diagram
L-phenylalanine + H2O + O2
phenylpyruvate + NH3 + H2O2
show the reaction diagram
L-phenylalanine + O2 + H2O
3-phenylpyruvic acid + ammonia + H2O2
show the reaction diagram
L-Pro + H2O + O2
?
show the reaction diagram
-
-
-
-
?
L-Ser + H2O + O2
2-oxo-3-hydroxypropionic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Trp + H2O + O2
indol-3-pyruvate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Trp + H2O + O2
indole-3-pyruvate + NH3 + H2O2
show the reaction diagram
L-tryptophan + H2O + O2
3-(1H-indol-3-yl)-2-oxopropanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-tryptophan + H2O + O2
3-(1H-indol-3-yl)-2-oxopropanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Tyr + H2O + O2
4-hydroxyphenylpyruvate + NH3 + H2O2
show the reaction diagram
L-tyrosine + H2O + O2
4-hydroxyphenylpyruvate + NH3 + H2O2
show the reaction diagram
L-Val + H2O + O2
2-oxoisovalerate + NH3 + H2O2
show the reaction diagram
L-valine + H2O + O2
2-oxoisovalerate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
lysine + H2O + O2
6-amino-2-oxohexanoic acid + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
additional information
?
-