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1.4.3.1: D-aspartate oxidase

This is an abbreviated version!
For detailed information about D-aspartate oxidase, go to the full flat file.

Word Map on EC 1.4.3.1

Reaction

D-Aspartate
+
H2O
 +
O2
=
oxaloacetate
 +
NH3
 +
H2O2

Synonyms

aspartic oxidase, C47A10.5 gene product, C47Ap, ChDASPO, ChDDO, D-Asp oxidase, D-aspartic oxidase, D-AspO, DAO, DASOX, DASPO, DDO, DDO-1, DDO-2, DDO-3, DDO1, DDO3, F18E3.7a gene product, F18Ep

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.1 D-aspartate oxidase

IC50 Value

IC50 Value on EC 1.4.3.1 - D-aspartate oxidase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.86
(5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methyl-1,3-butadienyl]-2(5H)-thiophenone
Mus musculus
-
pH 8.3, 37°C
1
1-hydroxy-1H-indole-2-carboxylic acid
Homo sapiens
IC50 above 1 mM, at pH 8.3 and 37°C
10
2-amino-5-chlorobenzoic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
1
2-aminopyridine-3-carboxylic acid
Homo sapiens
IC50 above 1 mM, at pH 8.3 and 37°C
0.1
2-aminopyridine-4-carboxylic acid
Homo sapiens
IC50 above 0.1 mM, at pH 8.3 and 37°C
10
2-hydroxy-6-methylpyridine-3-carboxylic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
10
3-aminobenzoic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
1
3-aminopyridine-2-carboxylic acid
Homo sapiens
IC50 above 1 mM, at pH 8.3 and 37°C
5
3-aminopyridine-4-carboxylic acid
Homo sapiens
IC50 above 5 mM, at pH 8.3 and 37°C
10
3-hydroxypyridine-2-carboxylic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
0.1
4-aminopyridine-2-carboxylic acid
Homo sapiens
IC50 above 0.1 mM, at pH 8.3 and 37°C
0.1
4-aminopyridine-3-carboxylic acid
Homo sapiens
IC50 above 0.1 mM, at pH 8.3 and 37°C
5
4-carbamoylthiophene-2-carboxylic acid
Homo sapiens
IC50 above 5 mM, at pH 8.3 and 37°C
1
5-(dimethylamino)pyridine-3-carboxylic acid
Homo sapiens
IC50 above 1 mM, at pH 8.3 and 37°C
3.541
5-(methylamino)pyridine-3-carboxylic acid
Homo sapiens
at pH 8.3 and 37°C
10
5-(trifluoromethyl)pyridine-3-carboxylic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
0.0219
5-aminonicotinic acid
Homo sapiens
at pH 8.3 and 37°C
10
5-aminopyridine-2-carboxylic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
10
5-bromopyridine-3-carboxylic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
10
5-chloro-2-hydroxybenzoic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
10
5-chloropyridine-3-carboxylic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
10
5-fluoro-2-hydroxybenzoic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
10
5-fluoropyridine-3-carboxylic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
3.351
5-hydroxypyridine-3-carboxylic acid
Homo sapiens
at pH 8.3 and 37°C
10
5-methoxypyridine-3-carboxylic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
5.472
5-methylpyridine-3-carboxylic acid
Homo sapiens
at pH 8.3 and 37°C
10
5-nitropyridine-3-carboxylic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
5
5-phenylpyridine-3-carboxylic acid
Homo sapiens
IC50 above 5 mM, at pH 8.3 and 37°C
10
5-sulfopyridine-3-carboxylic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
0.1
6-aminopyridine-2-carboxylic acid
Homo sapiens
IC50 above 0.1 mM, at pH 8.3 and 37°C
2.364
6-aminopyridine-3-carboxylic acid
Homo sapiens
at pH 8.3 and 37°C
5.3
malonate
Mus musculus
-
pH 8.3, 37°C
8.71
meso-tartrate
Mus musculus
-
pH 8.3, 37°C
0.0014 - 0.0231
olanzapine
10
pyridin-3-amine
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
10
pyridine-3,5-dicarboxylic acid
Homo sapiens
IC50 above 10 mM, at pH 8.3 and 37°C
2.778
pyridine-3-carboxylic acid
Homo sapiens
at pH 8.3 and 37°C