1.4.2.1: glycine dehydrogenase (cytochrome)

This is an abbreviated version!
For detailed information about glycine dehydrogenase (cytochrome), go to the full flat file.

Reaction

glycine
+
H2O
+
2 ferricytochrome c
=
glyoxylate
+
NH3
+ 2 ferrocytochrome c + 2 H+

Synonyms

dehydrogenase, glycine (cytochrome), glycine-cytochrome c reductase, reductase, glycine-cytochrome c

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.2 With a cytochrome as acceptor
                1.4.2.1 glycine dehydrogenase (cytochrome)

Inhibitors

Inhibitors on EC 1.4.2.1 - glycine dehydrogenase (cytochrome)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Cu2+
-
55% inhibition at 1 mM
cytochrome c
-
above 0.15 mM
diphosphate
-
buffer, 10 mM
EDTA
-
64% inhibition at 7.1 mM
hydroxylamine
-
-
KCl
-
80% inhibition at 75 mM
KCN
-
47% inhibition at 7.1 mM
KNO3
-
80% inhibition at 75 mM
MgCl2
-
80% inhibition at 40 mM
NaCl
-
80% inhibition at 75 mM
phosphate
-
buffer, 100 mM
pyridoxal 5'-phosphate
-
up to 80% inhibition at 0.2-2 mM due to reaction with glycine
pyruvate
-
70% inhibition at 10 mM and 20% inhibition at 3 mM
Quinacrine hydrochloride
-
0.3-1.0 mM
Sodium azide
-
10% inhibition at 2 mM
sodium barbital
-
buffer, 100 mM, pH 8.0
Tris
-
buffer, 100 mM, pH 8.0
Urea
-
30% inhibition at 50 mM