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1.4.1.8: valine dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about valine dehydrogenase (NADP+), go to the full flat file.

Reaction

L-valine
+
H2O
+
NADP+
=
3-methyl-2-oxobutanoate
+
NH3
+
NADPH
+
H+

Synonyms

dehydrogenase, valine (nicotinamide adenine dinucleotide phosphate), ValDH, valine dehydrogenase (nicotinamide adenine dinucleotide phosphate), VDH

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.8 valine dehydrogenase (NADP+)

Cloned

Cloned on EC 1.4.1.8 - valine dehydrogenase (NADP+)

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
valDH gene cloned to identify the active site, coding region expressed in Escherichia coli using a pET expression system
-
vdh gene
vdh gene encoding VDH2, only one gene responsible for VDH activity, VDH2 is the only active VDH
-