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1.4.1.28: secondary-alkyl amine dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about secondary-alkyl amine dehydrogenase [NAD(P)+], go to the full flat file.

Reaction

a secondary-alkyl amine
+
H2O
+
NAD(P)+
=
a ketone
+
NH3
+
NAD(P)H
+
H+

Synonyms

AMDH, AmDH4, amine dehydrogenase, D187_009359, DapB_1, NAD+-dependent amine dehydrogenase, Pmob_1166

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.28 secondary-alkyl amine dehydrogenase [NAD(P)+]

Turnover Number

Turnover Number on EC 1.4.1.28 - secondary-alkyl amine dehydrogenase [NAD(P)+]

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2.5
(2R)-2-amino-4-oxopentanoate
mutant E102A, pH 9.5, 23°C
0.32 - 1.79
1-hydroxybutan-2-one
0.61
2-methylcyclohexanone
pH 9.5, 23°C
0.13 - 13
cyclohexanone
0.11 - 0.54
Isobutanal
0.1 - 0.58
NADH
0.05 - 0.28
NADPH
0.04 - 37.8
NH3