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1.4.1.27: glycine cleavage system

This is an abbreviated version!
For detailed information about glycine cleavage system, go to the full flat file.

Word Map on EC 1.4.1.27

Reaction

glycine
+
tetrahydrofolate
 +
NAD+
=
5,10-methylenetetrahydrofolate
 +
NH3
 +
CO2
 +
NADH

Synonyms

Amt, At1g11860, At1g32470, At1g48030, AT2G35370, At4g33010, DLD, DLDH, GCSH, GCV, GcvH, GcvP, GCVT, GDCSH, GDCSP, GDH1, GDSCT, GLDC, glycine cleavage complex, H-protein, LpdA, P-protein, sll0171, slr1096, T-protein

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.27 glycine cleavage system

Engineering

Engineering on EC 1.4.1.27 - glycine cleavage system

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
S67F
mutation in H-protein, significant decrease in activity
S67P
mutation in H-protein, increase in activity
S67Q
mutation in H-protein, significant decrease in activity
S67T
mutation in H-protein, increase in activity
S67V
mutation in H-protein, increase in activity
S67Y
mutation in H-protein, significant decrease in activity
additional information