1.4.1.20: phenylalanine dehydrogenase

This is an abbreviated version!
For detailed information about phenylalanine dehydrogenase, go to the full flat file.

Reaction

Synonyms

dehydrogenase, phenylalanine, L-PheDH, L-phenylalanine dehydrogenase, L-phenylalanine:NAD+ oxidoreductase, deaminating, PDH, PHD, PheDH, phenylalanine dehydrogenase, recombinant PheDH, recombinant phenylalanine dehydrogenase

ECTree

     1 Oxidoreductases

         1.4 Acting on the CH-NH₂ group of donors

             1.4.1 With NAD⁺ or NADP⁺ as acceptor

                1.4.1.20 phenylalanine dehydrogenase

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Results	in table
7	Activating Compound
41	AA Sequence
17	Application
1	CAS Registry Number
21	Cloned(Commentary)
85	Cofactor
7	Crystallization (Commentary)
1	General Information
8	General Stability
60	Inhibitors
38	kcat/KM [mM/s]
15	Ki Value [mM]
177	KM Value [mM]
3	Localization
1	Metals/Ions
32	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
6	Organic Solvent Stability
82	Organism
5	Pathway
4	PDB ID
27	pH Optimum
3	pH Range
10	pH Stability
1	Posttranslational Modification
49	Protein Variants
24	Purification (Commentary)
4	Reaction
3	Reaction Type
70	Reference
2	Source Tissue
18	Specific Activity [micromol/min/mg]
4	Storage Stability
228	Substrates and Products (Substrate)
25	Subunits
33	Synonyms
1	Systematic Name
16	Temperature Optimum [°C]
6	Temperature Range [°C]
30	Temperature Stability [°C]
82	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.4.1.20 - phenylalanine dehydrogenase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

L-Phe + H2O + NAD+

phenylpyruvate + NH3 + NADH

Brevibacterium sp.

-

the enzyme is involved in the degradation of Phe

349639

-

349639

?

L-phenylalanine + H2O + NAD+

phenylpyruvate + NH3 + NADH

2 entries

L-phenylalanine + H2O + NAD+

phenylpyruvate + NH3 + NADH + H+

8 entries

phenylpyruvate + NH3 + NADH

L-phenylalanine + H2O + NAD+

Lysinibacillus sphaericus

-

-

656887

-

-

?

L-phenylalanine + H2O + NAD+

phenylpyruvate + NH3 + NADH

Bacillus badius

-

-

654620

-

-

r

L-phenylalanine + H2O + NAD+

phenylpyruvate + NH3 + NADH

Lysinibacillus sphaericus

-

-

654620, 655468, 657404

-

-

r

L-phenylalanine + H2O + NAD+

phenylpyruvate + NH3 + NADH + H+

Fictibacillus nanhaiensis

A0A1B1PGG4

-

743108

-

-

?

L-phenylalanine + H2O + NAD+

phenylpyruvate + NH3 + NADH + H+

Fictibacillus nanhaiensis DSF-15A2

A0A1B1PGG4

-

743108

-

-

?

L-phenylalanine + H2O + NAD+

phenylpyruvate + NH3 + NADH + H+

Rhodococcus sp.

-

-

725742

-

-

r

L-phenylalanine + H2O + NAD+

phenylpyruvate + NH3 + NADH + H+

Rhodococcus sp.

Q59771

-

741482

-

-

?

L-phenylalanine + H2O + NAD+

phenylpyruvate + NH3 + NADH + H+

Rhodococcus sp. 4

-

-

725742

-

-

r

L-phenylalanine + H2O + NAD+

phenylpyruvate + NH3 + NADH + H+

Sporosarcina sp.

-

-

743098

-

-

r

L-phenylalanine + H2O + NAD+

phenylpyruvate + NH3 + NADH + H+

Sporosarcina ureae

-

-

723965

-

-

r

L-phenylalanine + H2O + NAD+

phenylpyruvate + NH3 + NADH + H+

Thermoactinomyces intermedius

P22823

-

741735

-

-

?