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1.4.1.17: N-methylalanine dehydrogenase

This is an abbreviated version!
For detailed information about N-methylalanine dehydrogenase, go to the full flat file.

Reaction

N-Methyl-L-alanine
+
H2O
+
NADP+
=
pyruvate
+
methylamine
+
NADPH
+
H+

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.17 N-methylalanine dehydrogenase

Substrates Products

Substrates Products on EC 1.4.1.17 - N-methylalanine dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
methylamine + alpha-ketobutyrate + NADPH
glutamic acid + H2O + NADP+
show the reaction diagram
-
14% of activity with pyruvate
-
-
?
methylamine + oxaloacetate + NADPH
aspartic acid + H2O + NADP+
show the reaction diagram
-
64% of activity with pyruvate
-
-
?
pyruvate + methylamine + NADPH
N-methyl-L-alanine + H2O + NADP+
show the reaction diagram
-
reverse reaction only to limited extend at very low rate
-
r