1.4.1.16: diaminopimelate dehydrogenase

This is an abbreviated version!
For detailed information about diaminopimelate dehydrogenase, go to the full flat file.

Reaction

Synonyms

BAB07799, BF3690, DAPDH, DDH, meso-2,6-diaminopimelate dehydrogenase, meso-alpha,epsilon-diaminopimelate dehydrogenase, meso-DAPDH, meso-diaminopimelate dehydrogenase, NADP+-dependent meso-diaminopimelate dehydrogenase, Sth1425, Theth_1310

ECTree

     1 Oxidoreductases

         1.4 Acting on the CH-NH₂ group of donors

             1.4.1 With NAD⁺ or NADP⁺ as acceptor

                1.4.1.16 diaminopimelate dehydrogenase

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Results	in table
3529	AA Sequence
4	Application
1	CAS Registry Number
20	Cloned(Commentary)
84	Cofactor
8	Crystallization (Commentary)
4	General Information
5	IC50 Value
77	Inhibitors
77	kcat/KM [mM/s]
10	Ki Value [mM]
133	KM Value [mM]
1	Metals/Ions
15	Molecular Weight [Da]
49	Natural Substrates/ Products (Substrates)
120	Organism
6	Pathway
38	PDB ID
21	pH Optimum
3	pH Range
4	pH Stability
52	Protein Variants
18	Purification (Commentary)
5	Reaction
3	Reaction Type
111	Reference
34	Specific Activity [micromol/min/mg]
5	Storage Stability
211	Substrates and Products (Substrate)
17	Subunits
42	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
12	Temperature Stability [°C]
102	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 1.4.1.16 - diaminopimelate dehydrogenase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0149

(5S)-5-[(2S)-2-amino-2-carboxyethyl]-4,5-dihydro-1,2-oxazole-3-carboxylic acid

Porphyromonas gingivalis

Q7MW40

pH 7.8, temperature not specified in the publication

762799

1.164

2-[(3S,4S)-3-carboxy-4-propylpyrrolidin-1-yl]-6-methylpyridine-3-carboxylic acid

Porphyromonas gingivalis

Q7MW40

at pH 10.5 and 25°C

743593

0.157

3-([3-[(4-methoxybenzene-1-sulfonyl)amino]quinoxalin-2-yl]amino)benzoic acid

Porphyromonas gingivalis

Q7MW40

at pH 10.5 and 25°C

743593

0.31

3-([4-[(3,4-dimethylbenzene-1-sulfonyl)amino]-1-hydroxynaphthalen-2-yl]sulfanyl)propanoic acid

Porphyromonas gingivalis

Q7MW40

at pH 10.5 and 25°C

743593

0.356

4-oxo-4-[4-[(quinoxalin-2-yl)sulfamoyl]anilino]butanoic acid

Porphyromonas gingivalis

Q7MW40

at pH 10.5 and 25°C

743593