1.4.1.15: lysine dehydrogenase

This is an abbreviated version!
For detailed information about lysine dehydrogenase, go to the full flat file.

Word Map on EC 1.4.1.15

1.4.1.15

saccharopine

pipecolate

pomeroyi

6-dehydrogenase

silicibacter

analysis

Reaction

Synonyms

L-lysine epsilon dehydrogenase, LysDH

ECTree

1 Oxidoreductases

1.4 Acting on the CH-NH₂ group of donors

1.4.1 With NAD⁺ or NADP⁺ as acceptor

1.4.1.15 lysine dehydrogenase

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Results	in table
22	Activating Compound
1	Application
1	CAS Registry Number
5	Cofactor
1	Expression
2	General Information
1	Inhibitors
3	KM Value [mM]
3	Natural Substrates/ Products (Substrates)
126	Organism
3	pH Optimum
1	Purification (Commentary)
2	Reaction
4	Reaction Type
120	Reference
1	Source Tissue
20	Specific Activity [micromol/min/mg]
38	Substrates and Products (Substrate)
1	Subunits
2	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
2	Temperature Stability [°C]

Natural Substrates Products

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Natural Substrates Products on EC 1.4.1.15 - lysine dehydrogenase

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L-lysine + NAD+

1,2-didehydropiperidine-2-carboxylate + NH3 + NADH

Homo sapiens

391496

L-lysine + NAD+

1,2-didehydropiperidine-2-carboxylate + NH3 + NADH + H+

Ruegeria pomeroyi

725167

L-lysine + NAD+ + H2O

1,2-didehydropiperidine-6-carboxylate + NH3 + NADH

Agrobacterium tumefaciens

epsilon amino group is oxidatively deaminated to alpha-aminoadipate delta-semialdehyde, which is spontaneously converted into 1,2-didehydropiperidine-6-carboxylate, first step of lysine degradation

391497