Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.4.1.14: glutamate synthase (NADH)

This is an abbreviated version!
For detailed information about glutamate synthase (NADH), go to the full flat file.

Wordmap for 1.4.1.14

Word Map on EC 1.4.1.14 Wordmap for 1.4.1.14

Reaction

2 L-glutamate +

Show molfile
NAD+
=
Show molfile
L-glutamine
+
Show molfile
2-oxoglutarate
+
Show molfile
NADH
+
Show molfile
H+

Synonyms

gltA, GltA2, gltB, glutamate (reduced nicotinamide adenine dinucleotide) synthase, glutamate synthase, glutamate synthase (NADH), glutamate synthase (NADH-dependent), glutamate synthetase, glutamine 2-oxoglutarate aminotransferase, GOGAT, GOGAT1, GOGAT2, L-glutamate synthase (NADH), L-glutamate synthetase, NADH glutamate synthase, NADH-dependent glutamate synthase, NADH-dependent glutamine-2-oxoglutarate aminotransferase, NADH-GltS, NADH-glutamate synthase, NADH-GOGAT, NADH-GOGAT I, NADH-GOGAT II, NADH-GOGAT1, NADH-GOGAT2, NADH: GOGAT, Os01g0681900, Os05g0555600, synthase, glutamate (reduced nicotinamide adenine dinucleotide)

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                EC 1.4.1.141.4.1.14 glutamate synthase (NADH)

Reference

Reference on EC 1.4.1.14 - glutamate synthase (NADH)

for references in articles please use BRENDA:EC1.4.1.14

Please use the Reference Search for a specific query.

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Meister, A.
Glutamate synthase from Escherichia coli, Klebsiella aerogenes, and Saccharomyces cerevisiae
Methods Enzymol.
113
327-337
1985
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Boland, M.J.; Benny, A.G.
Enzymes of nitrogen metabolism in legume nodules. Purification and properties of NADH-dependent glutamate synthase from lupin nodules
Eur. J. Biochem.
79
355-362
1977
Lupinus angustifolius
Manually annotated by BRENDA team
Hayakawa, T.; Yamaya, T.; Kamachi, K.; Ojima, K.
Purification, characterization, and immunological properties of NADH-dependent glutamate synthase from rice cell cultures
Plant Physiol.
98
1317-1322
1992
Oryza sativa
Manually annotated by BRENDA team
Anderson, M.P.; Vance, C.P.; Heichel, G.H.; Miller, S.S.
Purification and characterization of NADH-glutamate synthase from alfalfa root nodules
Plant Physiol.
90
351-358
1989
Medicago sativa
Manually annotated by BRENDA team
Chen, F.L.; Cullimore, J.V.
Two isoenzymes of NADH-dependent glutamate synthase in root nodules of Phaseolus vulgaris L.. Purification, properties and activity changes during nodule development
Plant Physiol.
88
1411-1417
1988
Phaseolus vulgaris
Manually annotated by BRENDA team
Singhal, R.K.; Krishnan, I.S.; Dua, R.D.
Stabilization, purification, and characterization of glutamate synthase from Clostridium pasteurianum
Biochemistry
28
7928-7935
1989
Clostridium pasteurianum
Manually annotated by BRENDA team
Masters, D.S.; Meister, A.
Inhibition by homocysteine sulfonamide of glutamate synthase purified from Saccharomyces cerevisiae
J. Biol. Chem.
257
8711-8715
1982
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Romero, D.; Davila, G.
Genetic and biochemical identification of the glutamate synthase structural gene in Neurospora crassa
J. Bacteriol.
167
1043-1047
1986
Neurospora crassa
Manually annotated by BRENDA team
Wang, R.; Nicholas, D.J.D.
Some properties of glutamine synthetase and glutamate synthase from Derxia gummosa
Phytochemistry
24
1133-1139
1985
Derxia gummosa
-
Manually annotated by BRENDA team
Khanna, S.; Nicholas, D.J.D.
Some properties of glutamine synthetase and glutamate synthase from Chlorobium vibrioforme f. thiosulfatophilum
Arch. Microbiol.
134
98-103
1983
Prosthecochloris vibrioformis f. thiosulfatophilum, Prosthecochloris vibrioformis f. thiosulfatophilum NCIB 8346
-
Manually annotated by BRENDA team
Boland, M.J.; Court, C.B.
Glutamate synthase (NADH) from lupin nodules. Specificity of the 2-oxoglutarate site
Biochim. Biophys. Acta
657
539-542
1981
Lupinus angustifolius
Manually annotated by BRENDA team
Hummelt, G.; Mora, J.
NADH-dependent glutamate synthase and nitrogen metabolism in Neurospora crassa
Biochem. Biophys. Res. Commun.
92
127-133
1980
Neurospora crassa, Neurospora crassa am-1
Manually annotated by BRENDA team
Miyatake, K.; Kitaoka, S.
NADH-dependent glutamate synthase in Euglena gracilis z
Agric. Biol. Chem.
45
1727-1729
1981
Euglena gracilis, Euglena gracilis Z
-
Manually annotated by BRENDA team
Boland, M.J.
NADH-dependent glutamate synthase from lupin nodules. Reactions with oxidised and reduced 3-acetylpyridine-adenine dinucleotide
Eur. J. Biochem.
115
485-489
1981
Lupinus angustifolius
Manually annotated by BRENDA team
Marquez, A.J.; Galvan, F.; Vega, J.M.
Purification and characterization of the NADH-glutamate synthase from Chlamydomonas reinhardii
Plant Sci. Lett.
34
305-314
1984
Chlamydomonas reinhardtii, Chlamydomonas reinhardtii 21 gr
-
Manually annotated by BRENDA team
Roon, R.J.; Even, H.I.; Larimore, F.
Glutamate synthase: Properties of the reduced nicotinamide adenine dinucleotide-dependent enzyme from Saccharomyces cerevisiae
J. Bacteriol.
118
89-95
1974
Saccharomyces cerevisiae, Saccharomyces cerevisiae X2180A
Manually annotated by BRENDA team
Boland, M.J.
Kinetic mechanism of NADH-dependent glutamate synthase from lupin nodules
Eur. J. Biochem.
99
531-539
1979
Lupinus angustifolius
Manually annotated by BRENDA team
Cordovilla, M.P.; Perez, J.; Ligero, F.; Lluch, C.; Valpuesta, V.
Partial purification and characterization of NADH-glutamate synthase from faba bean (Vicia faba) root nodules
Plant Sci.
150
121-128
2000
Vicia faba
-
Manually annotated by BRENDA team
Ishiyama, K.; Hayakawa, T.; Yamaya, T.
Expression of NADH-dependent glutamate synthase protein in the epidermis and exodermis of rice roots in response to the supply of ammonium ions
Planta
204
288-294
1998
Oryza sativa
Manually annotated by BRENDA team
Hayakawa, T.; Hopkins, L.; Peat, L.J.; Yamaya, T.; Tobin, A.K.
Quantitative intercellular localization of NADH-dependent glutamate synthase protein in different types of root cells in rice plants
Plant Physiol.
119
409-416
1999
Oryza sativa
Manually annotated by BRENDA team
Obara, M.; Kajiura, M.; Fukuta, Y.; Yano, M.; Hayashi, M.; Yamaya, T.; Sato, T.
Mapping of QTLs associated with cytosolic glutamine synthetase and NADH-glutamate synthase in rice (Oriza sativa L.)
J. Exp. Bot.
52
1209-1217
2001
Oryza sativa
Manually annotated by BRENDA team
Doverskog, M.; Jacobsson, U.; Chapman, B.E.; Kuchel, P.W.; Häggström, L.
Determination of NADH-dependent glutamate synthase (GOGAT) in Spodoptera frugiperda (Sf9) insect cells by a selective 1H/15N NMR in vitro assay
J. Biotechnol.
79
87-97
2000
Bombyx mori, Spodoptera frugiperda, Spodoptera frugiperda Sf9
Manually annotated by BRENDA team
Vanoni, M.A.; Curti, B.
Glutamate synthase: A complex iron-sulfur flavoprotein
Cell. Mol. Life Sci.
55
617-638
1999
Bombyx mori, Caenorhabditis elegans, Medicago sativa, Plasmodium falciparum, Saccharomyces cerevisiae
Manually annotated by BRENDA team
Vance, C.P.; Miller, S.S.; Gregerson, D.L.; Samac, D.A.; Robinson, D.L.; Gantt, J.S.
Alfalfa NADH-dependent glutamate synthase: Structure of the gene and importance in symbiotic N2 fixation
Plant J.
8
345-358
1995
Medicago sativa
Manually annotated by BRENDA team
Chichkova, S.; Arellano, J.; Vance, C.P.; Hernandez, G.
Transgenic tobacco plants that overexpress alfalfa NADH-glutamate synthase have higher carbon and nitrogen content
J. Exp. Bot.
52
2079-2087
2001
Medicago sativa, Nicotiana tabacum, Oryza sativa
Manually annotated by BRENDA team
Cullimore, J.V.; Sims, A.P.
Occurrence of two forms of glutamate synthase in Chlamydomonas reinhardii
Phytochemistry
20
597-600
1981
Chlamydomonas reinhardtii, Chlamydomonas reinhardtii CCAP 11/32A
-
Manually annotated by BRENDA team
Lancien, M.; Martin, M.; Hsieh, M.H.; Leustek, T.; Goodman, H.; Coruzzi, G.M.
Arabidopsis glt1-T mutant defines a role for NADH-GOGAT in the non-photorespiratory ammonium assimilatory pathway
Plant J.
29
347-358
2002
Arabidopsis thaliana (Q9LV03)
Manually annotated by BRENDA team
Cordoba, E.; Shishkova, S.; Vance, C.P.; Hernandez, G.
Antisense inhibition of NADH glutamate synthase impairs carbon/nitrogen assimilation in nodules of alfalfa (Medicago sativa L.)
Plant J.
33
1037-1049
2003
Medicago sativa
Manually annotated by BRENDA team
Ishiyama, K.; Kojima,S.; Takahashi, H.; Hayakawa, T.; Yamaya, T.
Cell type distinct accumulations of mRNA and protein for NADH-dependent glutamate synthase in rice roots in response to the supply of NH4+
Plant Physiol. Biochem.
41
643-647
2003
Oryza sativa
-
Manually annotated by BRENDA team
Abiko, T.; Obara, M.; Ushioda, A.; Hayakawa, T.; Hodges, M.; Yamaya, T.
Localization of NAD-isocitrate dehydrogenase and glutamate dehydrogenase in rice roots: candidates for providing carbon skeletons to NADH-glutamate synthase
Plant Cell Physiol.
46
1724-1734
2005
Oryza sativa
Manually annotated by BRENDA team
Masclaux-Daubresse, C.; Reisdorf-Cren, M.; Pageau, K.; Lelandais, M.; Grandjean, O.; Kronenberger, J.; Valadier, M.H.; Feraud, M.; Jouglet, T.; Suzuki, A.
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco
Plant Physiol.
140
444-456
2006
Nicotiana tabacum
Manually annotated by BRENDA team
Feraud, M.; Masclaux-Daubresse, C.; Ferrario-Mery, S.; Pageau, K.; Lelandais, M.; Ziegler, C.; Leboeuf, E.; Jouglet, T.; Viret, L.; Spampinato, A.; Paganelli, V.; Hammouda, M.B.; Suzuki, A.
Expression of a ferredoxin-dependent glutamate synthase gene in mesophyll and vascular cells and functions of the enzyme in ammonium assimilation in Nicotiana tabacum (L.)
Planta
222
667-677
2005
Nicotiana tabacum
Manually annotated by BRENDA team
Chao, L.; Bofu, P.; Weiqian, C.; Yun, L.; Hao, H.; Liang, C.; Xiaoqing, L.; Xiao, W.; Fashui, H.
Influences of calcium deficiency and cerium on growth of spinach plants
Biol. Trace Elem. Res.
121
266-275
2008
Spinacia oleracea
Manually annotated by BRENDA team
Menard, A.; Monnez, C.; Estrada de Los Santos, P.; Segonds, C.; Caballero-Mellado, J.; Lipuma, J.J.; Chabanon, G.; Cournoyer, B.
Selection of nitrogen-fixing deficient Burkholderia vietnamiensis strains by cystic fibrosis patients: involvement of nif gene deletions and auxotrophic mutations
Environ. Microbiol.
9
1176-1185
2007
Burkholderia vietnamiensis
Manually annotated by BRENDA team
Valadier, M.H.; Yoshida, A.; Grandjean, O.; Morin, H.; Kronenberger, J.; Boutet, S.; Raballand, A.; Hase, T.; Yoneyama, T.; Suzuki, A.
Implication of the glutamine synthetase/glutamate synthase pathway in conditioning the amino acid metabolism in bundle sheath and mesophyll cells of maize leaves
FEBS J.
275
3193-3206
2008
Zea mays
Manually annotated by BRENDA team
Jain, M.; Pal, M.; Gupta, P.; Gadre, R.
Effect of cadmium on chlorophyll biosynthesis and enzymes of nitrogen assimilation in greening maize leaf segments: role of 2-oxoglutarate
Indian J. Exp. Biol.
45
385-389
2007
Zea mays
Manually annotated by BRENDA team
Vanoni, M.A.; Curti, B.
Structure-function studies of glutamate synthases: a class of self-regulated iron-sulfur flavoenzymes essential for nitrogen assimilation
IUBMB Life
60
287-300
2008
Aedes aegypti, Anopheles gambiae, Bombyx mori, Caenorhabditis elegans, Ciona intestinalis, Drosophila melanogaster, Plasmodium falciparum
Manually annotated by BRENDA team
Whittaker, A.; Martinelli, T.; Farrant, J.M.; Bochicchio, A.; Vazzana, C.
Sucrose phosphate synthase activity and the co-ordination of carbon partitioning during sucrose and amino acid accumulation in desiccation-tolerant leaf material of the C4 resurrection plant Sporobolus stapfianus during dehydration
J. Exp. Bot.
58
3775-3787
2007
Sporobolus stapfianus
Manually annotated by BRENDA team
Blanco, L.; Reddy, P.M.; Silvente, S.; Bucciarelli, B.; Khandual, S.; Alvarado-Affantranger, X.; Sanchez, F.; Miller, S.; Vance, C.; Lara-Flores, M.
Molecular cloning, characterization and regulation of two different NADH-glutamate synthase cDNAs in bean nodules
Plant Cell Environ.
31
454-472
2008
Phaseolus vulgaris
Manually annotated by BRENDA team
Tsujimoto, R.; Yamazaki, H.; Maeda, S.; Omata, T.
Distinct roles of nitrate and nitrite in regulation of expression of the nitrate transport genes in the moss Physcomitrella patens
Plant Cell Physiol.
48
484-497
2007
Physcomitrium patens
Manually annotated by BRENDA team
Yan, D.
Protection of the glutamate pool concentration in enteric bacteria
Proc. Natl. Acad. Sci. USA
104
9475-9480
2007
Escherichia coli, Salmonella enterica
Manually annotated by BRENDA team
Hayakawa, T.; Ishiyama, K.; Yamaya, T.
Tissue and cellular localization of NADH-dependent glutamate synthase protein in leaves of spinach
Tohoku J. Agric. Res.
57
1-11
2007
Spinacia oleracea
-
Manually annotated by BRENDA team
Potel, F.; Valadier, M.H.; Ferrario-Mery, S.; Grandjean, O.; Morin, H.; Gaufichon, L.; Boutet-Mercey, S.; Lothier, J.; Rothstein, S.J.; Hirose, N.; Suzuki, A.
Assimilation of excess ammonium into amino acids and nitrogen translocation in Arabidopsis thaliana - roles of glutamate synthases and carbamoylphosphate synthetase in leaves
FEBS J.
276
4061-4076
2009
Arabidopsis thaliana
Manually annotated by BRENDA team
Krog, A.; Heggeset, T.M.; Ellingsen, T.E.; Brautaset, T.
Functional characterization of key enzymes involved in L-glutamate synthesis and degradation in the thermotolerant and methylotrophic bacterium Bacillus methanolicus
Appl. Environ. Microbiol.
79
5321-5328
2013
Bacillus methanolicus, Bacillus methanolicus ATCC 53907
Manually annotated by BRENDA team
Hossain, M.; Uddin, M.; Ismail, M.; Ashrafuzzaman, M.
Responses of glutamine synthetase-glutamate synthase cycle enzymes in tomato leaves under salinity stress
Int. J. Agric. Biol.
14
509-515
2012
Solanum lycopersicum, Solanum lycopersicum BINATomato-5
-
Manually annotated by BRENDA team
SLu, Y.; Luo, F.; Yang, M.; Li, X.; Lian, X.
Suppression of glutamate synthase genes significantly affects carbon and nitrogen metabolism in rice (Oryza sativa L.)
Sci. China Life Sci.
54
651-663
2011
Oryza sativa Japonica Group (B9FLJ1), Oryza sativa Japonica Group (Q0JKD0)
Manually annotated by BRENDA team
Khouja, H.; Daghino, S.; Abbą, S.; Boutaraa, F.; Chalot, M.; Blaudez, D.; Martino, E.; Perotto, S.
OmGOGAT-disruption in the ericoid mycorrhizal fungus Oidiodendron maius induces reorganization of the N pathway and reduces tolerance to heavy-metals
Fungal Genet. Biol.
71
1-8
2015
Oidiodendron maius
Manually annotated by BRENDA team
Yamaya, T.; Kusano, M.
Evidence supporting distinct functions of three cytosolic glutamine synthetases and two NADH-glutamate synthases in rice
J. Exp. Bot.
65
5519-5525
2014
Oryza sativa
Manually annotated by BRENDA team
Konishi, N.; Ishiyama, K.; Matsuoka, K.; Maru, I.; Hayakawa, T.; Yamaya, T.; Kojima, S.
NADH-dependent glutamate synthase plays a crucial role in assimilating ammonium in the Arabidopsis root
Physiol. Plant.
152
138-151
2014
Arabidopsis thaliana
Manually annotated by BRENDA team
Kojima, S.; Konishi, N.; Beier, M.P.; Ishiyama, K.; Maru, I.; Hayakawa, T.; Yamaya, T.
NADH-dependent glutamate synthase participated in ammonium assimilation in Arabidopsis root
Plant Signal. Behav.
9
e29402
2014
Arabidopsis thaliana
Manually annotated by BRENDA team
Garcia-Gutierrez, A.; Canovas, F.M.; Avila, C.
Glutamate synthases from conifers gene structure and phylogenetic studies
BMC Genomics
19
65
2018
Pinus pinaster (A0A3G1HH65), Pinus pinaster
Manually annotated by BRENDA team
Imagawa, F.; Minagawa, H.; Nakayama, Y.; Kanno, K.; Hayakawa, T.; Kojima, S.
Tos17 insertion in NADH-dependent glutamate synthase genes leads to an increase in grain protein content in rice
J. Cereal Sci.
84
38-43
2018
Oryza sativa Japonica Group (Q0DG35), Oryza sativa Japonica Group (Q0JKD0)
-
Manually annotated by BRENDA team
Jiao, Y.; Chen, Y.; Ma, C.; Qin, J.; Nguyen, T.H.N.; Liu, D.; Gan, H.; Ding, S.; Luo, Z.B.
Phenylalanine as a nitrogen source induces root growth and nitrogen-use efficiency in Populus x canescens
Tree Physiol.
38
66-82
2018
Populus tremula x Populus alba (A1Y9J3)
Manually annotated by BRENDA team