Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.4.1.14: glutamate synthase (NADH)

This is an abbreviated version!
For detailed information about glutamate synthase (NADH), go to the full flat file.

Wordmap for 1.4.1.14

Word Map on EC 1.4.1.14 Wordmap for 1.4.1.14

Reaction

2 L-glutamate +

Show molfile
NAD+
=
Show molfile
L-glutamine
+
Show molfile
2-oxoglutarate
+
Show molfile
NADH
+
Show molfile
H+

Synonyms

gltA, GltA2, gltB, glutamate (reduced nicotinamide adenine dinucleotide) synthase, glutamate synthase, glutamate synthase (NADH), glutamate synthase (NADH-dependent), glutamate synthetase, glutamine 2-oxoglutarate aminotransferase, GOGAT, GOGAT1, GOGAT2, L-glutamate synthase (NADH), L-glutamate synthetase, NADH glutamate synthase, NADH-dependent glutamate synthase, NADH-dependent glutamine-2-oxoglutarate aminotransferase, NADH-GltS, NADH-glutamate synthase, NADH-GOGAT, NADH-GOGAT I, NADH-GOGAT II, NADH-GOGAT1, NADH-GOGAT2, NADH: GOGAT, Os01g0681900, Os05g0555600, synthase, glutamate (reduced nicotinamide adenine dinucleotide)

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                EC 1.4.1.141.4.1.14 glutamate synthase (NADH)

Activating Compound

Activating Compound on EC 1.4.1.14 - glutamate synthase (NADH)

for references in articles please use BRENDA:EC1.4.1.14

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
-
1%, presence of a reducing agent is essential for enzyme activity
diphosphate
-
5 mM, stimulates activity with 36% enhancement
dithiothreitol
-
0.5 mg per ml, presence of a reducing agent is essential for enzyme activity
GltB
-
GltA and not GltA2 is dependent on GltB for GOGAT activity in vivo
-
NaNO3
-
transcripts for NADH-GOGAT transiently accumulate when 1 mM is applied
NH4Cl
-
NADH-GOGAT gene expression is transiently induced within a few hours of supplying either 1 or 25 mM to the medium, leading to a marked accumulation of NADH-GOGAT mRNA
NH4NO3
-
transcripts for NADH-GOGAT transiently accumulate when 0.5 mM is applied
succinate
-
50 mM, stimulates activity by 57%
additional information
-