3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)

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Word Map on EC


a 3-oxo-5alpha-steroid
a 3-oxo-DELTA4-steroid
reduced acceptor


dehydrogenase, 3-oxo-5alphasteroid DELTA4-, steroid 5alpha-reductase, 3-oxosteroid DELTA4-dehydrogenase, 3-oxo-5alpha-steroid DELTA4-dehydrogenase, steroid DELTA4-5alpha-reductase, DELTA4-3-keto steroid 5alpha-reductase, DELTA4-3-oxo steroid reductase, DELTA4-3-ketosteroid 5alpha-oxidoreductase, DELTA4-3-oxosteroid-5alpha-reductase, 3-keto-DELTA4-steroid-5 alpha-reductase, 5alpha-reductase, testosterone 5alpha-reductase, 4-ene-3-ketosteroid-5alpha-oxidoreductase, DELTA4-5alpha-dehydrogenase, 3-ketosteroid-DELTA4(5alpha)-dehydrogenase, DELTA4(5alpha)DH, 5 alpha-SR2, S5AR, 5alpha-R, steroid 5alpha-reductase type 1, 5alpha-R1, S5alphaRI, S5alphaRII, SRD5A1, SRD5A2, 5alphaR1, 5alphaR2, 5alpha-reductase II, 5alpha-reductase type 1, 5alpha-reductase type 2, 5-alpha reductase II, type 2 5alpha-reductase, type 1 5alpha-reductase, 5alpha-reductase type II, steroid 5alpha-reductase type 2, steroid-5alpha-reductase, SRD5alpha, 5alpha-reductase type1, 5alpha-reductase type2, type II 5alpha-reductase, 5AR2, 3-oxo-steroid-4-ene dehydrogenase, type I 5alpha-reductase, NADPH-dependent 5alpha-reductase enzyme, steroid 5-alpha reductase type 2, r5alphaR1, steroid 5-alpha-reductase type 2, 5alpha reductase


     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.99 With unknown physiological acceptors
       3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)


Expression on EC - 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)

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17beta-estradiol administered to spayed females induces the up-regulation of Srd5a2 mRNA levels
Srd5a2 is induced in livers and prostate from mice fed a chow diet supplemented with lovastatin plus ezitimibe, which increases the activity of nuclear SREBP-2, induction of Srd5a2 through SREBP-2, SREBP-2 binds to the promoter for Srd5a2