1.3.99.4: 3-oxosteroid 1-dehydrogenase

This is an abbreviated version!
For detailed information about 3-oxosteroid 1-dehydrogenase, go to the full flat file.

Word Map on EC 1.3.99.4

Reaction

a 3-oxosteroid
+
acceptor
=
a 3-oxo-DELTA1-steroid
+
reduced acceptor

Synonyms

1-ene-dehydrogenase, 3-keto-5alpha-steroid DELTA(1)-dehydrogenase, 3-ketosteroid 1(2)-dehydrogenase, 3-ketosteroid delta1-dehydrogenase, 3-ketosteroid-1-en-dehydrogenase, 3-ketosteroid-D1-dehydrogenase, 3-ketosteroid-DELTA1-dehydrogenase, 3-oxosteroid D1-dehydrogenase, 3-oxosteroid Delta1-dehydrogenase, 3-oxosteroid:(2,6-dichlorphenolindophenol) DELTA1-oxidoreductase, 3-oxosteroid:(2,6-dichlorphenolindophenol)D1-oxidoreductase, 4-en-3-oxosteroid:(acceptor)-1-en-oxido-reductase, 4-ene-3-oxosteroid: (acceptor)-1-ene-oxoreductase, 4-ene-3-oxosteroid:(acceptor)l-ene-oxidoreductase, D1-dehydrogenase, D1-steroid reductase, dehydrogenase, 3-oxo steroid Delta 1-, Delta1-dehydrogenase, DELTA1-KSTD1, DELTA1-steroid reductase, ketosteroid DELTA1-dehydrogenase, KsdD, KsdD1, KsdD2, KsdDM, KSDH, KstD, KSTD1, KSTD2, KSTD3, KSTD3 orthologue, KstDF, Rv3537, steroid-1-dehydrogenase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.99 With unknown physiological acceptors
                1.3.99.4 3-oxosteroid 1-dehydrogenase

KM Value

KM Value on EC 1.3.99.4 - 3-oxosteroid 1-dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0246
(5alpha,17beta)-17-hydroxyandrostan-3-one
pH 7.0, 30°C
0.0064
11-deoxy-17alpha-hydroxycorticosterone
-
i.e. 4-pregnene-17alpha,21-diol-3,20-dione
0.0196
11alpha-hydroxyprogesterone
-
i.e. 4-pregnene-11alpha-ol-3,20-dione, 11beta-hydroxy-4-androstene-3,17-dione, 4-estren-3,17-dione
0.064 - 0.557
11beta-cortisol
0.0063
11beta-hydroxytestosterone
-
i.e. 4-androstene-11beta,17beta-diol-3-one
0.0089
19-nor-4-androstene-3,17-dione
-
i.e. 4-estren-3,17-dione
0.0083
19-nortestosterone
-
4-estren-17beta-ol-3one
0.3474 - 0.3688
19alpha-hydroxy-4-androstene-3,17-dione
-
0.026 - 0.074
23,24-bis-nor-5alpha-cholestan-3-one acid
0.011 - 0.085
4-androstene-17beta-ol-3-one
0.005 - 0.335
4-androstene-3,17-dione
0.0382 - 0.0761
4-pregnen-3-one-20beta-carboxylic acid
-
0.006 - 0.166
5alpha-androstan-3-one-17beta-ol
0.035 - 0.0379
5alpha-androstane-17beta-ol-3-one
0.013 - 0.059
5alpha-androstane-3,17-dione
0.007 - 0.021
5alpha-pregnane-3,20-dione
0.0221 - 0.5432
9alpha-hydroxy-4-androstene-3,17-dione
0.045
androstenedione
-
-
0.0066
androsterone
-
i.e. 4-androstene-3,11,17-trione
0.0204 - 0.3743
corticosterone
0.0256
cortisone
-
i.e. 4-pregnene-17alpha,21diol-3,11,20-trione
0.0216 - 0.1113
deoxycorticosterone
0.000075
FAD
-
-
0.0385
hydrocorticosterone
-
i.e. 4-pregnene-11beta,17alpha,21-triol-3,20-dione
0.003 - 0.125
progesterone
0.0143
testololactone
-
i.e. 17alpha-oxo-D-homo-1,4-androstadiene-3,17-dione
0.0288 - 0.1811
testosterone
additional information
additional information
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