1.3.99.23: all-trans-retinol 13,14-reductase

This is an abbreviated version!
For detailed information about all-trans-retinol 13,14-reductase, go to the full flat file.

Word Map on EC 1.3.99.23

Reaction

all-trans-13,14-dihydroretinol
+
acceptor
=
all-trans-retinol
+
reduced acceptor

Synonyms

(13,14)-all-trans-retinol saturase, 13,14-dihydroretinol saturase, all-trans-13,14-dihydroretinol saturase, all-trans-retinol:all-trans-13,14-dihydroretinol saturase, retinol saturase, RetSat, RetSat A

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.99 With unknown physiological acceptors
                1.3.99.23 all-trans-retinol 13,14-reductase

Disease

Disease on EC 1.3.99.23 - all-trans-retinol 13,14-reductase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Congenital Abnormalities
Identification of genes related to beak deformity of chickens using digital gene expression profiling.
Diabetes Mellitus, Type 2
Retinol Saturase: More than the Name Suggests.
Fatty Liver
Retinol saturase coordinates liver metabolism by regulating ChREBP activity.
Hyperglycemia
Retinol saturase coordinates liver metabolism by regulating ChREBP activity.
Insulin Resistance
Integration of heterogeneous expression data sets extends the role of the retinol pathway in diabetes and insulin resistance.
Retinol Saturase: More than the Name Suggests.
Metabolic Diseases
Retinol saturase promotes adipogenesis and is downregulated in obesity.
Metabolic Syndrome
Retinol saturase coordinates liver metabolism by regulating ChREBP activity.
Obesity
Retinol saturase promotes adipogenesis and is downregulated in obesity.
Sarcoma
Case Report: Exome sequencing reveals recurrent RETSAT mutations and a loss-of-function POLDIP2 mutation in a rare undifferentiated tongue sarcoma.