1.3.98.7: [mycofactocin precursor peptide]-tyrosine decarboxylase

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For detailed information about [mycofactocin precursor peptide]-tyrosine decarboxylase, go to the full flat file.

Reaction

C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-L-tyrosine

C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-4-[2-aminoethenyl]phenol

Synonyms

mftC, MtfC, mycofactocin maturase, Rv0693

ECTree

1 Oxidoreductases

1.3 Acting on the CH-CH group of donors

1.3.98 With other, known, physiological acceptors

1.3.98.7 [mycofactocin precursor peptide]-tyrosine decarboxylase

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Results	in table
4	AA Sequence
1	Cloned(Commentary)
2	Cofactor
7	General Information
1	Metals/Ions
2	Natural Substrates/ Products (Substrates)
16	Organism
1	Pathway
8	Protein Variants
1	Purification (Commentary)
1	Reaction
10	Reference
8	Substrates and Products (Substrate)
20	Synonyms
1	Systematic Name

Cofactor

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Cofactor on EC 1.3.98.7 - [mycofactocin precursor peptide]-tyrosine decarboxylase

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S-adenosyl-L-methionine

Mycobacterium ulcerans

A0PM49

residues Cys30, 34, and 37 are the radical S-adenosylmethionine ligands

760607

[4Fe-4S]-center

Mycobacterium ulcerans

A0PM49

MftC binds a radical S-adenosylmethionine [4Fe-4S] cluster and two auxiliary [4Fe-4S] clusters that are required for MftA modification. Presence of S-adenosylmethionine and MftA affects the environments of the radical S-adenosylmethionine and Aux I cluster whereas the Aux II cluster is unaffected by the substrates. All three cluster are required for cataylsis

760607