1.3.8.3: (R)-benzylsuccinyl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about (R)-benzylsuccinyl-CoA dehydrogenase, go to the full flat file.

Reaction

Synonyms

bbgS, BbsG, EC 1.3.99.21

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.8 With a flavin as acceptor

                1.3.8.3 (R)-benzylsuccinyl-CoA dehydrogenase

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Results	in table
880	AA Sequence
1	CAS Registry Number
4	Cloned(Commentary)
11	Cofactor
2	General Information
1	Inhibitors
3	KM Value [mM]
2	Molecular Weight [Da]
12	Natural Substrates/ Products (Substrates)
19	Organism
6	Pathway
3	pH Optimum
1	Purification (Commentary)
1	Reaction
3	Reaction Type
17	Reference
3	Specific Activity [micromol/min/mg]
15	Substrates and Products (Substrate)
6	Subunits
20	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 1.3.8.3 - (R)-benzylsuccinyl-CoA dehydrogenase

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SYSTEMATIC NAME

IUBMB Comments

(R)-benzylsuccinyl-CoA:electron transfer flavoprotein oxidoreductase

Requires FAD as prosthetic group. Unlike other acyl-CoA dehydrogenases, this enzyme exhibits high substrate- and enantiomer specificity; it is highly specific for (R)-benzylsuccinyl-CoA and is inhibited by (S)-benzylsuccinyl-CoA. Forms the third step in the anaerobic toluene metabolic pathway in Thauera aromatica. Ferricenium ion is an effective artificial electron acceptor.