1.3.8.3: (R)-benzylsuccinyl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about (R)-benzylsuccinyl-CoA dehydrogenase, go to the full flat file.

Reaction

(R)-2-benzylsuccinyl-CoA
+
electron-transfer flavoprotein
=
(E)-2-benzylidenesuccinyl-CoA
+
reduced electron-transfer flavoprotein

Synonyms

BbsG

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.8 With a flavin as acceptor
                1.3.8.3 (R)-benzylsuccinyl-CoA dehydrogenase

Systematic Name

Systematic Name on EC 1.3.8.3 - (R)-benzylsuccinyl-CoA dehydrogenase

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SYSTEMATIC NAME
IUBMB Comments
(R)-benzylsuccinyl-CoA:electron transfer flavoprotein oxidoreductase
Requires FAD as prosthetic group. Unlike other acyl-CoA dehydrogenases, this enzyme exhibits high substrate- and enantiomer specificity; it is highly specific for (R)-benzylsuccinyl-CoA and is inhibited by (S)-benzylsuccinyl-CoA. Forms the third step in the anaerobic toluene metabolic pathway in Thauera aromatica. Ferricenium ion is an effective artificial electron acceptor.