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1.3.8.1: short-chain acyl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about short-chain acyl-CoA dehydrogenase, go to the full flat file.

Word Map on EC 1.3.8.1

Reaction

a short-chain acyl-CoA
+
electron-transfer flavoprotein
=
a short-chain trans-2,3-dehydroacyl-CoA
+
reduced electron-transfer flavoprotein

Synonyms

3-hydroxyacyl CoA reductase, ACADS, Acfer_0556, Acfer_1477, acyl-CoA dehydrogenase short chain, BCAD, BCD, bcd2, BcdAf, bSCAD, butyryl CoA dehydrogenase, butyryl coenzyme A dehydrogenase, butyryl-CoA dehydrogenase, butyryl-CoA dehydrogenase complex, butyryl-CoA dehydrogenase/Etf complex, CD1054, dehydrogenase, butyryl coenzyme A, EC 1.3.2.1, EC 1.3.99.2, enoyl-coenzyme A reductase, ethylene reductase, HADHSC, non-dissociating bifurcating Etf-Bcd complex, SCAD, ScdA, short chain acyl-CoA dehydrogenase, short-chain 3-hydroxyacyl-CoA dehydrogenase, short-chain acyl CoA dehydrogenase, short-chain acyl-CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, short-chain acylCoA dehydrogenase, unsaturated acyl coenzyme A reductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.8 With a flavin as acceptor
                1.3.8.1 short-chain acyl-CoA dehydrogenase

Natural Substrates Products

Natural Substrates Products on EC 1.3.8.1 - short-chain acyl-CoA dehydrogenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
2-butenoyl-CoA + reduced acceptor
butanoyl-CoA + acceptor
show the reaction diagram
-
reduction in vivo
-
-
r
2-butenoyl-CoA + reduced electron transfer flavoprotein
butanoyl-CoA + electron transfer protein
show the reaction diagram
-
enzyme functions as C3-C6 enoyl-CoA reductase in vivo and catalyzes the oxidation of butyryl-CoA and related substrates in vitro
-
r
2-hexenoyl-CoA + reduced electron transfer flavoprotein
hexanoyl-CoA + electron transfer protein
show the reaction diagram
-
enzyme functions as C3-C6 enoyl-CoA reductase in vivo and catalyzes the oxidation of butyryl-CoA and related substrates in vitro
-
r
2-pentenoyl-CoA + reduced electron transfer flavoprotein
pentanoyl-CoA + electron transfer protein
show the reaction diagram
-
enzyme functions as C3-C6 enoyl-CoA reductase in vivo and catalyzes the oxidation of butyryl-CoA and related substrates in vitro
-
r
2-propenoyl-CoA + reduced electron transfer flavoprotein
propanoyl-CoA + electron transfer protein
show the reaction diagram
-
enzyme functions as C3-C6 enoyl-CoA reductase in vivo and catalyzes the oxidation of butyryl-CoA and related substrates in vitro
-
r
butanoyl-CoA + acceptor
but-2-enoyl-CoA + reduced acceptor
show the reaction diagram
butanoyl-CoA + oxidized acceptor
crotonyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
-
r
crotonyl-CoA + 2 NADH + 2 Fd-
butyryl-CoA + 2 NAD+ + 2 Fd2-
show the reaction diagram
hexanoyl-CoA + acceptor
hex-2-enoyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
?
pentanoyl-CoA + acceptor
pent-2-enoyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
?
additional information
?
-
-
catalyzes the first step in the beta-oxidation cycle with substrate optima of 4 carbon chains
-
-
?