1.3.5.6: 9,9'-dicis-zeta-carotene desaturase

This is an abbreviated version!
For detailed information about 9,9'-dicis-zeta-carotene desaturase, go to the full flat file.

Word Map on EC 1.3.5.6

Reaction

7,9,9'-tricis-neurosporene
+
a quinone
=
7,9,7',9'-tetracis-lycopene
+
a quinol

Synonyms

CrtI, CrtQa, CrtQb, phytoene desaturase, ZDS, zeta-carotene desaturase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.5 With a quinone or related compound as acceptor
                1.3.5.6 9,9'-dicis-zeta-carotene desaturase

Natural Substrates Products

Natural Substrates Products on EC 1.3.5.6 - 9,9'-dicis-zeta-carotene desaturase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
7,9,9'-tricis-neurosporene + a quinone
7,9,7',9'-tetracis-lycopene + a quinol
show the reaction diagram
9,9'-dicis-zeta-carotene + 2 quinone
7,9,7',9'-tetracis-lycopene + 2 quinol
show the reaction diagram
9,9'-dicis-zeta-carotene + a quinone
7,9,9'-tricis-neurosporene + a quinol
show the reaction diagram
neurosporene + a quinone
lycopene + a quinol
show the reaction diagram
-
-
-
-
?
phytoene + quinone
7,9,9'-tricis-neurosporene + quinol
show the reaction diagram
zeta-carotene + 2 AH2 + 2 O2
lycopene + 2 A + 4 H2O
show the reaction diagram
zeta-carotene + 2 quinone
lycopene + 2 quinol
show the reaction diagram
-
zeta-carotene desaturase has no preference for certain isomers. The nature of the isomers formed during catalysis depends strictly on the isomeric composition of the substrate. Different lycopene isomers are formed, including substantial amounts of the all-trans form, together with 7,7',9,9'-tetracis prolycopene via the corresponding neurosporene isomers
-
-
?
zeta-carotene + a quinone
neurosporene + a quinol
show the reaction diagram
-
-
-
-
?
zeta-carotene + AH2 + O2
neurosporene + A + H2O
show the reaction diagram
Q2PPX8
-
-
-
?
additional information
?
-
-
strain PCC 7120 contains two completely unrelated zeta-carotene desaturases CrtQa and CrtQb, which differ in their preferred utilization of zeta-carotene Z isomers. CrtQa con­verts zeta-carotene isomers that are poorly metabolized by CrtQb and CrtQa still possesses the Z to E isomerase function of the ancestral desaturase CrtI. CrtQb is an enzyme with one molecule of tightly bound FAD and acts as a dehydrogenase transferring hydrogen to oxidized plastoquinone. CrtQb yields only trace amounts of 7,9-Z neurosporene and 7,9,7',9'-Z lycopene
-
-
-