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1.3.5.6: 9,9'-dicis-zeta-carotene desaturase

This is an abbreviated version!
For detailed information about 9,9'-dicis-zeta-carotene desaturase, go to the full flat file.

Word Map on EC 1.3.5.6

Reaction

7,9,9'-tricis-neurosporene
+
a quinone
=
7,9,7',9'-tetracis-lycopene
+
a quinol

Synonyms

Carotene 7,8-desaturase, carotene desaturase, CrtI, CrtQa, CrtQb, Desaturase, zeta-carotene, Desaturase, zeta-carotene (Capsicum annuum clone pCapZDS precursor reduced), Desaturase, zeta-carotene (Nostoc muscorum clone pZDS1A reduced), Desaturase, zeta-carotene (Synechocystis strain PCC 6803 clone cs0223/cs0128/ps0014/cs0681/cs0294 gene ctrQ-2 reduced), EC 1.14.99.30, EutZds, genBank D90914-derived protein GI 1653487, phytoene desaturase, ZDS, ZDS/SPC1, ZDS1, ZDS2, zeta-carotene desaturase, zeta-carotene desaturase (Anabaena strain PCC 7120 clone pZDS1A), zeta-carotene desaturase (Capsicum annuum clone pCapZDS precursor reduced), zeta-carotene desaturase (Synechocystis strain PCC 6803 gene crtQ-2), zeta-carotene desaturase 1, zeta-carotene desaturase 2

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.5 With a quinone or related compound as acceptor
                1.3.5.6 9,9'-dicis-zeta-carotene desaturase

Engineering

Engineering on EC 1.3.5.6 - 9,9'-dicis-zeta-carotene desaturase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
E508G
-
random mutagenesis, the mutation has little effect on the enzyme activity
F166I
-
random mutagenesis, a beneficial mutation that helps the conversion of product from neurosporene to lycopene
F220S
-
random mutagenesis, the mutation has little effect on the enzyme activity
H12Q
-
random mutagenesis, the mutation has little effect on the enzyme activity
L148H
-
random mutagenesis, the beneficial mutation is highly increasing the production of lycopene to over 80%
M402T
-
random mutagenesis, the mutation reduces the lycopene production rate
V68D
-
random mutagenesis, a beneficial mutation that helps the conversion of product from neurosporene to lycopene
D355G
-
naturally occuring mutation
D53G
-
naturally occuring mutation
L153P
-
naturally occuring mutation, which influences the secondary structure of the enzyme
L208F
-
naturally occuring mutation, which influences the secondary structure of the enzyme
L208P
-
naturally occuring mutation, which influences the secondary structure of the enzyme
L278P
-
naturally occuring mutation, which influences the secondary structure of the enzyme
L424P
-
naturally occuring mutation, which influences the secondary structure of the enzyme
P134L
-
naturally occuring mutation, which influences the secondary structure of the enzyme
T256M
-
naturally occuring mutation
V395A
-
naturally occuring mutation
Y44C
-
naturally occuring mutation
L153P
-
naturally occuring mutation, which influences the secondary structure of the enzyme
-
L208F
-
naturally occuring mutation, which influences the secondary structure of the enzyme
-
L208P
-
naturally occuring mutation, which influences the secondary structure of the enzyme
-
P134L
-
naturally occuring mutation, which influences the secondary structure of the enzyme
-
additional information