1.3.5.2: dihydroorotate dehydrogenase (quinone)

This is an abbreviated version!
For detailed information about dihydroorotate dehydrogenase (quinone), go to the full flat file.

Word Map on EC 1.3.5.2

Reaction

(S)-dihydroorotate
+
a quinone
=
Orotate
+
a quinol

Synonyms

class 2 dihydroorotate dehydrogenases, DHO-DH, DHOD, DHODase, DHODH, HsDHODH, L-5,6-dihydroorotate:ubiquinone exidoreductase, PfDHODH

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.5 With a quinone or related compound as acceptor
                1.3.5.2 dihydroorotate dehydrogenase (quinone)

Turnover Number

Turnover Number on EC 1.3.5.2 - dihydroorotate dehydrogenase (quinone)

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
38 - 86
(S)-dihydroorotate
29
1,4-Naphthoquinone
-
pH 8.0, 30°C
32
2,3-dimethoxy-5-methyl-1,4-benzoquinone
-
pH 8.0, 30°C
44
2,5-dimethyl-p-benzoquinone
-
pH 8.0, 30°C
5.7 - 9.3
Abz-VAA
0.19 - 7.8
coenzyme Q1
44.2
coenzyme Q6
-
-
0.12 - 12
coenzyme QD
1.8 - 89
decylubiquinone
1.4 - 72.9
dihydroorotate
1.4 - 16.1
L-dihydroorotate
18.3
menadione
-
-
45.4
methyl-dihydroorotate
-
-
0.083 - 0.63
O2
0.25 - 95
S-dihydroorotate
21
ubiquinone-30
-
pH 8.0, 30°C
1.8
ubiquinone-4
pH 8.0, 25°C, cosubstrate L-dihydroorotate, N-terminally truncated protein
61
ubiquinone-50
-
pH 8.0, 30°C
2
ubiquinone-6
pH 8.0, 25°C, cosubstrate L-dihydroorotate, N-terminally truncated protein
0.36
ubiquinone6
-
-
additional information
additional information
-
relative turnover numbers for wild-type and mutants listed for (S)-dihydroorotate and ubiquinone6
-