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1.3.3.5: bilirubin oxidase

This is an abbreviated version!
For detailed information about bilirubin oxidase, go to the full flat file.

Word Map on EC 1.3.3.5

Reaction

2 bilirubin +

O2
= 2 biliverdin + 2 H2O

Synonyms

bilirubin oxidase, bilirubin oxidase M-1, bilirubin:oxygen oxidoreductase, blue Cu enzyme, BOD, BODx, BOX, BPUM_0542, copper oxidase, CotA, MCO, multicopper oxidase, MvBO, MvBOD, oxidase, bilirubin

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.3 With oxygen as acceptor
                1.3.3.5 bilirubin oxidase

Substrates Products

Substrates Products on EC 1.3.3.5 - bilirubin oxidase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(4E,15Z)-cyclobilirubin IX alpha + O2
?
show the reaction diagram
-
phosphate buffer, pH 3.5-7.4
-
-
?
(4Z,15E)-bilirubin IX alpha + O2
?
show the reaction diagram
-
no activity above pH 4.5 in phosphate buffer
-
-
?
(4Z,15Z)-bilirubin IX alpha + O2
?
show the reaction diagram
-
no activity above pH 5.5 in phosphate buffer, no acticvity in citrate-lactate buffer, pH 3.7
-
-
?
1,1'-dimethylferrocene + O2
1,1'-dimethylferricenium + H2O
show the reaction diagram
-
1,1'-dimethylferrocene soluble as an inclusion complex with 2-hydroxypropyl-beta-cyclodextrin
-
?
1,3-dihydroxynaphthalene + O2
?
show the reaction diagram
-
-
-
-
?
1,5-dihydroxynaphthalene + O2
?
show the reaction diagram
-
-
-
-
?
2 bilirubin + O2
2 biliverdin + 2 H2O
show the reaction diagram
2 bilirubin + O2
2 biliverdin + H2O
show the reaction diagram
2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) + O2
?
show the reaction diagram
2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) + O2
? + H2O
show the reaction diagram
2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) + O2
oxidized 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) + H2O
show the reaction diagram
2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonate) + O2
?
show the reaction diagram
2,2'-azino-di-[3-ethylbenzthiazoline-6-sulfonic acid] + O2
?
show the reaction diagram
2,6-dimethoxyphenol + O2
? + H2O
show the reaction diagram
ascorbic acid + O2
?
show the reaction diagram
bilirubin + O2
biliverdin + H2O
show the reaction diagram
bilirubin ditaurine + O2
?
show the reaction diagram
-
-
-
-
?
biliverdin + O2
?
show the reaction diagram
catechol + O2
?
show the reaction diagram
-
67% of activity with bilirubin
-
-
?
chlorophyllin + O2
?
show the reaction diagram
-
50% of activity with bilirubin
-
-
?
Congo Red + O2
?
show the reaction diagram
cytochrome c + O2
?
show the reaction diagram
-
BOD efficiently accepts cytochrome c as an electron donor in both cases when cytochrome c is in solution or electrostatically adsorbed
-
-
?
ditaurobilirubin + O2
?
show the reaction diagram
Fe(CN)64- + O2
Fe(CN)63- + H2O
show the reaction diagram
-
-
-
-
?
ferricyanide + O2
? + H2O
show the reaction diagram
-
-
-
?
ferrocene + O2
ferricinium + H2O
show the reaction diagram
-
low activity
-
?
ferrocyanide + O2
?
show the reaction diagram
-
-
-
-
?
ferrocyanide + O2
ferricyanide + H2O
show the reaction diagram
hemin + O2
?
show the reaction diagram
-
10% of activity with bilirubin
-
-
?
hexacyanoferrate(II) + O2
hexacyanoferrate(III) + H2O
show the reaction diagram
-
-
-
-
?
hydroquinone + O2
?
show the reaction diagram
-
20% of activity with bilirubin
-
-
?
indigo carmine + O2
?
show the reaction diagram
-
dye decolorization reaction
-
-
?
K4[Fe(CN)6] + O2
K3[Fe(CN)6] + H2O
show the reaction diagram
-
-
-
-
?
N,N-dimethyl-p-phenylenediamine + O2
?
show the reaction diagram
o-aminophenol + O2
?
show the reaction diagram
octacyanotungstate(IV) + O2
octacyanotungstate(V) + H2O
show the reaction diagram
-
-
-
-
?
p-phenylenediamine + O2
?
show the reaction diagram
phenol 2,6-dimethoxyphenol + O2
?
show the reaction diagram
pyrogallol + O2
?
show the reaction diagram
-
10% of activity with bilirubin
-
-
?
Remazol Brilliant Blue + O2
?
show the reaction diagram
Remazol Brilliant Blue R + O2
?
show the reaction diagram
syringaldazine + O2
?
show the reaction diagram
-
-
-
-
?
syringaldazine + O2
oxidized syringaldazine + H2O
show the reaction diagram
[Fe(CN)6]4- + H+ + O2
[Fe(CN)6]3- + H2O
show the reaction diagram
-
-
-
-
?
additional information
?
-