1.3.3.17: benzylmalonyl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about benzylmalonyl-CoA dehydrogenase, go to the full flat file.

Reaction

Synonyms

iaaF

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.3 With oxygen as acceptor

                1.3.3.17 benzylmalonyl-CoA dehydrogenase

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Results	in table
1	Cloned(Commentary)
1	Cofactor
1	Inhibitors
1	Ki Value [mM]
1	KM Value [mM]
1	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
10	Organism
1	Purification (Commentary)
1	Reaction
2	Reference
11	Substrates and Products (Substrate)
2	Subunits
3	Synonyms
1	Systematic Name
1	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 1.3.3.17 - benzylmalonyl-CoA dehydrogenase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

(3-methyl)-butylmalonyl-CoA + O2

?

2 entries

benzylmalonyl-CoA + O2

(E)-cinnamoyl-CoA + CO2 + H2O2

4 entries

butylmalonyl-CoA + O2

?

2 entries

hexylmalonyl-CoA + O2

?

Aromatoleum aromaticum

-

low specific activity

764044

-

-

?

additional information

?

-

2 entries

(3-methyl)-butylmalonyl-CoA + O2

?

Aromatoleum aromaticum

-

low specific activity

764044

-

-

?

(3-methyl)-butylmalonyl-CoA + O2

?

Aromatoleum aromaticum EbN1

-

low specific activity

764044

-

-

?

benzylmalonyl-CoA + O2

(E)-cinnamoyl-CoA + CO2 + H2O2

Aromatoleum aromaticum

-

-

764044

-

-

ir

benzylmalonyl-CoA + O2

(E)-cinnamoyl-CoA + CO2 + H2O2

Aromatoleum aromaticum

-

high activity. The enzyme is enantiospecific in benzylmalonyl-CoA turnover

764044

-

-

ir

benzylmalonyl-CoA + O2

(E)-cinnamoyl-CoA + CO2 + H2O2

Aromatoleum aromaticum EbN1

-

-

764044

-

-

ir

benzylmalonyl-CoA + O2

(E)-cinnamoyl-CoA + CO2 + H2O2

Aromatoleum aromaticum EbN1

-

high activity. The enzyme is enantiospecific in benzylmalonyl-CoA turnover

764044

-

-

ir

butylmalonyl-CoA + O2

?

Aromatoleum aromaticum

-

low specific activity

764044

-

-

?

butylmalonyl-CoA + O2

?

Aromatoleum aromaticum EbN1

-

low specific activity

764044

-

-

?

additional information

?

-

Aromatoleum aromaticum

-

the enzyme is inert with ethylmalonyl-CoA, methylmalonyl-CoA and phenylpropionyl-CoA. The enzyme shows no activity with electron transfer flavoprotein or artificial dyes serving as electron acceptors like ferricenium cation or phenazine-methosulfate/dichlorophenyl-indophenol. The enzyme also does not convert cinnamoyl-CoA to either benzylmalonyl-CoA (with carboxylation) or phenylpropionyl-CoA (without carboxylation) by using dithionite-reduced benzyl or methyl viologen

764044

-

-

-

additional information

?

-

Aromatoleum aromaticum EbN1

-

the enzyme is inert with ethylmalonyl-CoA, methylmalonyl-CoA and phenylpropionyl-CoA. The enzyme shows no activity with electron transfer flavoprotein or artificial dyes serving as electron acceptors like ferricenium cation or phenazine-methosulfate/dichlorophenyl-indophenol. The enzyme also does not convert cinnamoyl-CoA to either benzylmalonyl-CoA (with carboxylation) or phenylpropionyl-CoA (without carboxylation) by using dithionite-reduced benzyl or methyl viologen

764044

-

-

-