1.3.3.16: oxazoline dehydrogenase

This is an abbreviated version!
For detailed information about oxazoline dehydrogenase, go to the full flat file.

Reaction

Synonyms

artG, azoline oxidase, Cyan7425_0520, cyanobactin oxidase, lynG, MbcC, mcaG, McbB, McbC, McbD, microcin B17 synthase, microcin B17-processing protein McbC, PatG, tenG, ThcOx, thiazoline oxidase, thiazoline oxidase/subtilisin-like protease

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.3 With oxygen as acceptor

                1.3.3.16 oxazoline dehydrogenase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
3	AA Sequence
1	Cofactor
2	Crystallization (Commentary)
3	General Information
2	Natural Substrates/ Products (Substrates)
4	Organism
2	Pathway
1	Purification (Commentary)
3	Reaction
4	Reference
7	Substrates and Products (Substrate)
1	Subunits
18	Synonyms
1	Systematic Name

Substrates Products

print visible entries

print all entries

Substrates Products on EC 1.3.3.16 - oxazoline dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Substrate/Product Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

a [protein]-(1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline + O2

a [protein]-(S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-thiazole + H2O2

2 entries

a [protein]-(S,S)-2-(C-substituted-aminomethyl)-4-acyl-2-oxazoline + O2

a [protein]-(S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-oxazole + H2O2

2 entries

a [protein]-(S,S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-2-oxazoline + O2

a [protein]-(S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-1,3-oxazole + H2O2

Escherichia coli

P23185

-

757653

-

-

?

additional information

?

-

2 entries

a [protein]-(1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline + O2

a [protein]-(S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-thiazole + H2O2

Escherichia coli

P23184; P23185; P23186

-

758460

-

-

?

a [protein]-(1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline + O2

a [protein]-(S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-thiazole + H2O2

Escherichia coli

P23185

-

757653

-

-

?

a [protein]-(S,S)-2-(C-substituted-aminomethyl)-4-acyl-2-oxazoline + O2

a [protein]-(S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-oxazole + H2O2

Escherichia coli

P23184; P23185; P23186

-

758460

-

-

?

a [protein]-(S,S)-2-(C-substituted-aminomethyl)-4-acyl-2-oxazoline + O2

a [protein]-(S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-oxazole + H2O2

Escherichia coli

P23185

-

757653

-

-

?

additional information

?

-

Escherichia coli

P23185

proposed general mechanism for McbC: an activated Tyr202 abstracts a proton from the A carbon of an azoline substrate, which results in E2 elimination of the antiproton from the B carbon and hydride transfer to FMN. Instead of a proton being provided to FMN by a general base to yield FMNH2, the negative charge on N1 of FMN may be stabilized by a salt bridge with Arg233

757653

-

-

-

additional information

?

-

Prochloron didemni

Q52QJ1

enzyme oxidizes the 2-thiazoline in patellamide precursor peptides

758209

-

-

-