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1.3.3.11: pyrroloquinoline-quinone synthase

This is an abbreviated version!
For detailed information about pyrroloquinoline-quinone synthase, go to the full flat file.

Word Map on EC 1.3.3.11

Reaction

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate
+ 3 O2 =
4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate
+ 2 H2O2 + 2 H2O

Synonyms

PqqC, PqqC/D, pyrroloquinoline quinone synthase C, pyrroloquinoline-quinone synthase, pyrroloquinoline/quinone synthesis protein C, quinoprotein dehydrogenase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.3 With oxygen as acceptor
                1.3.3.11 pyrroloquinoline-quinone synthase

Reference

Reference on EC 1.3.3.11 - pyrroloquinoline-quinone synthase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Toyama, H.; Fukumoto, H.; Saeki, M.; Matsushita, K.; Adachi, O.; Lidstrom, M.E.
PqqC/D, which converts a biosynthetic intermediate to pyrroloquinoline quinone
Biochem. Biophys. Res. Commun.
299
268-272
2002
Methylorubrum extorquens, Methylorubrum extorquens ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1
Manually annotated by BRENDA team
Khairnar, N.P.; Misra, H.S.; Apte, S.K.
Pyrroloquinoline-quinone synthesized in Escherichia coli by pyrroloquinoline-quinone synthase of Deinococcus radiodurans plays a role beyond mineral phosphate solubilization
Biochem. Biophys. Res. Commun.
312
303-308
2003
Deinococcus radiodurans, Deinococcus radiodurans KR1
Manually annotated by BRENDA team
Magnusson, O.T.; Toyama, H.; Saeki, M.; Schwarzenbacher, R.; Klinman, J.P.
The structure of a biosynthetic intermediate of pyrroloquinoline quinone (PQQ) and elucidation of the final step of PQQ biosynthesis
J. Am. Chem. Soc.
126
5342-5343
2004
Methylorubrum extorquens, Methylorubrum extorquens ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1
Manually annotated by BRENDA team
Toyama, H.; Chistoserdova, L.; Lidstrom, M.E.
Sequence analysis of pqq genes required for biosynthesis of pyrroloquinoline quinone in Methylobacterium extorquens AM1 and the purification of a biosynthetic intermediate
Microbiology
143
595-602
1997
Methylorubrum extorquens (Q49150), Methylorubrum extorquens ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1 (Q49150)
-
Manually annotated by BRENDA team
Magnusson, O.T.; Toyama, H.; Saeki, M.; Rojas, A.; Reed, J.C.; Liddington, R.C.; Klinman, J.P.; Schwarzenbacher, R.
Quinone biogenesis: Structure and mechanism of PqqC, the final catalyst in the production of pyrroloquinoline quinone
Proc. Natl. Acad. Sci. USA
101
7913-7918
2004
Klebsiella pneumoniae (P27505)
Manually annotated by BRENDA team
Schwarzenbacher, R.; Stenner-Liewen, F.; Liewen, H.; Reed, J.C.; Liddington, R.C.
Crystal structure of PqqC from Klebsiella pneumoniae at 2.1 ANG resolution
Proteins
56
401-403
2004
Klebsiella pneumoniae (P27505)
Manually annotated by BRENDA team
Toyama, H.; Nishibayashi, E.; Saeki, M.; Adachi, O.; Matsushita, K.
Factors required for the catalytic reaction of PqqC/D which produces pyrroloquinoline quinone
Biochem. Biophys. Res. Commun.
354
290-295
2007
Escherichia coli, Klebsiella pneumoniae, Methylorubrum extorquens, Methylorubrum extorquens ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1
Manually annotated by BRENDA team
Arakawa, K.; Sugino, F.; Kodama, K.; Ishii, T.; Kinashi, H.
Cyclization mechanism for the synthesis of macrocyclic antibiotic lankacidin in Streptomyces rochei
Chem. Biol.
12
249-256
2005
Streptomyces rochei
Manually annotated by BRENDA team
Magnusson, O.T.; RoseFigura, J.M.; Toyama, H.; Schwarzenbacher, R.; Klinman, J.P.
Pyrroloquinoline quinone biogenesis: characterization of PqqC and its H84N and H84A active site variants
Biochemistry
46
7174-7186
2007
Klebsiella pneumoniae
Manually annotated by BRENDA team
Puehringer, S.; Metlitzky, M.; Schwarzenbacher, R.
The pyrroloquinoline quinone biosynthesis pathway revisited: a structural approach
BMC Biochem.
9
8-8
2008
Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae (P27505)
Manually annotated by BRENDA team
Meyer, J.B.; Frapolli, M.; Keel, C.; Maurhofer, M.
Pyrroloquinoline quinone biosynthesis gene pqqC, a novel molecular marker for studying the phylogeny and diversity of phosphate-solubilizing pseudomonads
Appl. Environ. Microbiol.
77
7345-7354
2011
Pseudomonas sp.
Manually annotated by BRENDA team
Puehringer, S.; RoseFigura, J.; Metlitzky, M.; Toyama, H.; Klinman, J.P.; Schwarzenbacher, R.
Structural studies of mutant forms of the PQQ-forming enzyme PqqC in the presence of product and substrate
Proteins
78
2554-2562
2010
Klebsiella pneumoniae (A6T9H1), Klebsiella pneumoniae MGH 78578 (A6T9H1)
Manually annotated by BRENDA team
Wang, P.; Xia, Y.; Li, J.; Kang, Z.; Zhou, J.; Chen, J.
Overexpression of pyrroloquinoline quinone biosynthetic genes affects L-sorbose production in Gluconobacter oxydans WSH-003
Biochem. Eng. J.
112
70-77
2016
Gluconobacter oxydans (Q9L3B2), Gluconobacter oxydans WSH-003 (Q9L3B2)
-
Manually annotated by BRENDA team
Pietra, F.
On dioxygen permeation through a dehydrogenase-pyrroloquinoline quinone complex. A molecular-dynamics investigation
Chem. Biodivers.
11
209-216
2014
Klebsiella pneumoniae (P27505)
Manually annotated by BRENDA team
Xu, J.; Deng, P.; Showmaker, K.C.; Wang, H.; Baird, S.M.; Lu, S.E.
The pqqC gene is essential for antifungal activity of Pseudomonas kilonensis JX22 against Fusarium oxysporum f. sp. lycopersici
FEMS Microbiol. Lett.
353
98-105
2014
Pseudomonas kilonensis (W5XLY8), Pseudomonas kilonensis JX22 (W5XLY8)
Manually annotated by BRENDA team