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BRENDA support

1.3.1.91: tRNA-dihydrouridine20 synthase [NAD(P)+]

This is an abbreviated version!
For detailed information about tRNA-dihydrouridine20 synthase [NAD(P)+], go to the full flat file.

Word Map on EC 1.3.1.91

Reaction

5,6-dihydrouracil20 in tRNA
+
NAD(P)+
=
uracil20 in tRNA
+
NAD(P)H
+
H+

Synonyms

dihydrouridine synthase, dihydrouridine synthase 2, dihydrouridine synthase C, Dus, DUS 2, DUS2, Dus2p, DusA, DusB, DusC, EcoDusC, hDUS2, HsDus2, SMM1, tRNA-dihydrouridine synthase 2, tRNA-dihydrouridine synthases

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.91 tRNA-dihydrouridine20 synthase [NAD(P)+]

Source Tissue

Source Tissue on EC 1.3.1.91 - tRNA-dihydrouridine20 synthase [NAD(P)+]

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
isozyme Dus2 is upregulated
Manually annotated by BRENDA team
overexpression of hDUS2 in non–small cell lung carcinomas is identified by analysis of the gene-expression profiles
Manually annotated by BRENDA team
elevated hDus2 mRNA and protein levels
Manually annotated by BRENDA team