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1.3.1.86: crotonyl-CoA reductase

This is an abbreviated version!
For detailed information about crotonyl-CoA reductase, go to the full flat file.

Word Map on EC 1.3.1.86

Reaction

butanoyl-CoA
+
NADP+
=
(E)-but-2-enoyl-CoA
 +
NADPH
 +
H+

Synonyms

3-hydroxyacyl CoA reductase, acyl-CoA:NADP+ trans-2-oxidoreductase, bcd2, butanoyl-CoA:(acceptor) 2,3-oxidoreductase, butyryl coenzyme A dehydrogenase, butyryl dehydrogenase, butyryl-CoA dehydrogenase, butyryl-CoA dehydrogenase complex, CCR, CD1054, crotonyl CoA reductase, crotonyl coenzyme A reductase, crotonyl-CoA reductase, crotonyl-coenzyme A reductase, EgTER1, enoyl-coenzyme A reductase, ethylene reductase, short-chain acyl CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, trans-crotonyl CoA reductase, unsaturated acyl coenzyme A reductase, unsaturated acyl-CoA reductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.86 crotonyl-CoA reductase

Reference

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Reference on EC 1.3.1.86 - crotonyl-CoA reductase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Strom, K.A.; Kumar, S.
Activation and inhibition of crotonyl-coenzyme A reductase activity of bovine mammary fatty acid synthetase
J. Biol. Chem.
254
8159-8162
1979
Bos taurus
-
Manually annotated by BRENDA team
Maitra, S.K.; Kumar, S.
Crotonyl coenzyme A reductase activity of bovine mammary fatty acid synthetase
J. Biol. Chem.
249
111-117
1974
Bos taurus
Manually annotated by BRENDA team
Li, C.; Florova, G.; Akopiants, K.; Reynolds, K.A.
Crotonyl-coenzyme A reductase provides methylmalonyl-CoA precursors for monensin biosynthesis by Streptomyces cinnamonensis in an oil-based extended fermentation
Microbiology
150
3463-3472
2004
Streptomyces virginiae, Streptomyces collinus
Manually annotated by BRENDA team
Dodds, P.F.; Kumar, S.
Effects of coenzyme A and pH on the reactions catalyzed by lactating bovine mammary-gland fatty acid synthase
Biochem. Soc. Trans.
9
556-557
1981
Bos taurus
-
Manually annotated by BRENDA team
Fukui, T.; Abe, H.; Doi, Y.
Engineering of Ralstonia eutropha for production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from fructose and solid-state properties of the copolymer
Biomacromolecules
3
618-624
2002
Streptomyces virginiae
Manually annotated by BRENDA team
Wallace, K.K.; Bao, Z.Y.; Dai, H.; Digate, R.; Schuler, G.; Speedie, M.K.; Reynolds, K.A.
Purification of crotonyl-CoA reductase from Streptomyces collinus and cloning, sequencing and expression of the corresponding gene in Escherichia coli
Eur. J. Biochem.
233
954-962
1995
Streptomyces collinus
Manually annotated by BRENDA team
Liu, H.; Wallace, K.K.; Reynolds, K.A.
Linking diversity in evolutionary origin and stereospecificity for enoyl thioester reductases: determination and interpretation of the novel stereochemical course of reaction catalyzed by crotonyl CoA reductase from Streptomyces collinus
J. Am. Chem. Soc.
119
2973-2979
1997
Streptomyces collinus
-
Manually annotated by BRENDA team
Liu, Y.; Hazzard, C.; Eustaquio, A.S.; Reynolds, K.A.; Moore, B.S.
Biosynthesis of salinosporamides from alpha,beta-unsaturated fatty acids: implications for extending polyketide synthase diversity
J. Am. Chem. Soc.
131
10376-10377
2009
Salinispora tropica
Manually annotated by BRENDA team
Han, L.; Reynolds, K.A.
A novel alternate anaplerotic pathway to the glyoxylate cycle in streptomycetes
J. Bacteriol.
179
5157-5164
1997
Streptomyces collinus
Manually annotated by BRENDA team
Sun, W.-J.; Salmon, P.; Wilson, J.; Connors, N.
Crotonic acid-directed biosynthesis of the immunosuppressants produced by Streptomyces hygroscopicus var. ascomyceticus
J. Ferment. Bioeng.
86
261-265
1998
Streptomyces hygroscopicus subsp. ascomyceticus
-
Manually annotated by BRENDA team
Akopiants, K.; Florova, G.; Li, C.; Reynolds, K.A.
Multiple pathways for acetate assimilation in Streptomyces cinnamonensis
J. Ind. Microbiol. Biotechnol.
33
141-150
2006
Streptomyces virginiae
Manually annotated by BRENDA team
Liu, H.; Reynolds, K.A.
Precursor supply for polyketide biosynthesis: the role of crotonyl-CoA reductase
Metab. Eng.
3
40-48
2001
Streptomyces virginiae
Manually annotated by BRENDA team
Stassi, D.L.; Kakavas, S.J.; Reynolds, K.A.; Gunawardana, G.; Swanson, S.; Zeidner, D.; Jackson, M.; Liu, H.; Buko, A.; Katz, L.
Ethyl-substituted erythromycin derivatives produced by directed metabolic engineering
Proc. Natl. Acad. Sci. USA
95
7305-7309
1998
Streptomyces collinus
Manually annotated by BRENDA team
Aboulnaga, e.l.-.H.; Pinkenburg, O.; Schiffels, J.; El-Refai, A.; Buckel, W.; Selmer, T.
Effect of an Oxygen-Tolerant Bifurcating Butyryl Coenzyme A Dehydrogenase/Electron-Transferring Flavoprotein Complex from Clostridium difficile on Butyrate Production in Escherichia coli
J. Bacteriol.
195
3704-3713
2013
Clostridioides difficile
Manually annotated by BRENDA team
Tomiyama, T.; Goto, K.; Tanaka, Y.; Maruta, T.; Ogawa, T.; Sawa, Y.; Ito, T.; Ishikawa, T.
A major isoform of mitochondrial trans-2-enoyl-CoA reductase is dispensable for wax ester production in Euglena gracilis under anaerobic conditions
PLoS ONE
14
e0210755
2019
Euglena gracilis (Q5EU90), Euglena gracilis
Manually annotated by BRENDA team