1.3.1.84: acrylyl-CoA reductase (NADPH)

This is an abbreviated version!
For detailed information about acrylyl-CoA reductase (NADPH), go to the full flat file.

Word Map on EC 1.3.1.84

1.3.1.84

propionyl-coa

acrylate

acuis

3-hydroxypropionate

3-hydroxypropionyl-coa

dehydratase

chloroflexus

sedula

crotonyl-coa

aurantiacus

ruegeria

dimethylsulfoniopropionate

metallosphaera

3-hydroxypropionate/4-hydroxybutyrate

hyper-sensitive

pomeroyi

lyases

dmdas

ethylmalonyl-coa

sphaeroides

roseobacters

succinyl-coa

synthesis

Reaction

Synonyms

Acr, acryloyl-CoA reductase, acryloyl-CoA reductase (NADPH), acryloyl-coenzyme A reductase, acrylyl-CoA reductase, acrylyl-coenzyme A reductase, AcuI, Msed_1426, NADPH-dependent acryloyl-CoA reductase activity, NADPH-dependent acrylyl-CoA reductase, RSP_1434, SPO1914, SPO_1914, yhdH

ECTree

1 Oxidoreductases

1.3 Acting on the CH-CH group of donors

1.3.1 With NAD⁺ or NADP⁺ as acceptor

1.3.1.84 acrylyl-CoA reductase (NADPH)

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Results	in table
6	Activating Compound
568	AA Sequence
2	Application
1	CAS Registry Number
8	Cloned(Commentary)
17	Cofactor
2	Expression
18	General Information
1	Inhibitors
7	kcat/KM [mM/s]
17	KM Value [mM]
1	Localization
9	Metals/Ions
13	Molecular Weight [Da]
20	Natural Substrates/ Products (Substrates)
16	Organism
9	Pathway
4	PDB ID
6	pH Optimum
1	pH Range
6	Protein Variants
8	Purification (Commentary)
3	Reaction
14	Reference
3	Source Tissue
13	Specific Activity [micromol/min/mg]
1	Storage Stability
34	Substrates and Products (Substrate)
13	Subunits
45	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
7	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 1.3.1.84 - acrylyl-CoA reductase (NADPH)

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propanoyl-CoA:NADP+ oxidoreductase

Catalyses a step in the 3-hydroxypropanoate/4-hydroxybutanoate cycle, an autotrophic CO2 fixation pathway found in some thermoacidophilic archaea [1]. The enzyme from Sulfolobus tokodaii does not act on either NADH or crotonyl-CoA [2]. Different from EC 1.3.1.8, which acts only on enoyl-CoA derivatives of carbon chain length 4 to 16. Contains Zn2+.