1.3.1.82: (-)-isopiperitenone reductase

This is an abbreviated version!
For detailed information about (-)-isopiperitenone reductase, go to the full flat file.

Word Map on EC 1.3.1.82

Reaction

(+)-cis-isopulegone
+
NADP+
=
(-)-isopiperitenone
+
NADPH
+
H+

Synonyms

More, isopiperitenone reductase, IPR, NADPH-dependent isopiperitenone reductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.82 (-)-isopiperitenone reductase

Systematic Name

Systematic Name on EC 1.3.1.82 - (-)-isopiperitenone reductase

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SYSTEMATIC NAME
IUBMB Comments
(+)-cis-isopulegone:NADP+ oxidoreductase
The reaction occurs in the opposite direction to that shown above. The enzyme participates in the menthol-biosynthesis pathway of Mentha plants. (+)-Pulegone, (+)-cis-isopulegone and (-)-menthone are not substrates. The enzyme has a preference for NADPH as the reductant, with NADH being a poor substitute [2]. The enzyme is highly regioselective for the reduction of the endocyclic 1,2-double bond, and is stereoselective, producing only the 1R-configured product. It is a member of the short-chain dehydrogenase/reductase superfamily.