1.3.1.8: acyl-CoA dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about acyl-CoA dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.3.1.8

Reaction

acyl-CoA
+
NADP+
=
2,3-dehydroacyl-CoA
+
NADPH
+
H+

Synonyms

2-enoyl-CoA reductase, 2-trans enoyl-CoA reductase, 2-trans-enoyl-CoA reductase, acyl coenzyme A dehydrogenase (nicotinamide adenine dinucleotide phosphate), CCR, crotonyl CoA reductase, crotonyl coenzyme A reductase, crotonyl-CoA reductase, crotonyl-coenzyme A reductase, dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate), enoyl coenzyme A reductase, enoyl-CoA reductase, MCAD, medium-chain acyl-CoA dehydrogenase, NADPH:enoyl-CoA oxidoreductase, NbECR, RCCR, trans-2-enoyl-CoA reductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.8 acyl-CoA dehydrogenase (NADP+)

Systematic Name

Systematic Name on EC 1.3.1.8 - acyl-CoA dehydrogenase (NADP+)

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SYSTEMATIC NAME
IUBMB Comments
acyl-CoA:NADP+ 2-oxidoreductase
The liver enzyme acts on enoyl-CoA derivatives of carbon chain length 4 to 16, with optimum activity on 2-hexenoyl-CoA. In Escherichia coli, cis-specific and trans-specific enzymes exist [EC 1.3.1.37 cis-2-enoyl-CoA reductase (NADPH) and EC 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)].