1.3.1.77: anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]

This is an abbreviated version!
For detailed information about anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming], go to the full flat file.

Word Map on EC 1.3.1.77

Reaction

a (2R,3R)-flavan-3-ol
+ 2 NAD(P)+ =
an anthocyanidin with a 3-hydroxy group
+ 2 NAD(P)H +
H+

Synonyms

AtANR, MtANR, ANR, anthocyanidin reductase, BAN, BANYULS, dihydroflavonol 4-reductase-like protein, BEN1, PtrANR1, CsANR, ANR1, ANR2, CsANR1, CsANR2, MdLAR1, FeANR, BpANR, RrANR, VbANR, GhANR1, anthocyanidin reductase 1, anthocyanidin reductase 2, ANR2a, ANRa, CssANRa, ANRb, CssANRb

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]

Systematic Name

Systematic Name on EC 1.3.1.77 - anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SYSTEMATIC NAME
IUBMB Comments
(2R,3R)-flavan-3-ol:NAD(P)+ 3,4-oxidoreductase
The enzyme participates in the flavonoid biosynthesis pathway found in plants. It catalyses the double reduction of anthocyanidins, producing (2R,3R)-flavan-3-ol monomers required for the formation of proanthocyanidins. While the enzyme from the legume Medicago truncatula (MtANR) can use both NADPH and NADH as reductant, that from the crucifer Arabidopsis thaliana (AtANR) uses only NADPH. Also, while the substrate preference of MtANR is cyanidin>pelargonidin>delphinidin, the reverse preference is found with AtANR. cf. EC 1.3.1.112, anthocyanidin reductase [(2S)-flavan-3-ol-forming].