1.3.1.74: 2-alkenal reductase [NAD(P)+]

This is an abbreviated version!
For detailed information about 2-alkenal reductase [NAD(P)+], go to the full flat file.

Word Map on EC 1.3.1.74

Reaction

a n-alkanal
+
NAD(P)+
=
an alk-2-enal
+
NAD(P)H
+
H+

Synonyms

2-alkenal reductase, 2AER, AER, alkenal/one oxidoreductase, alkenal/one reductase, AOR, At-AER, At5g16970, AtAOR, bifunctional LTB4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase, CS-670 double-bond reductase, CsAOR, Dbr1, double bond reductase, LTB4 12-HD/PGR, NADPH alkenal/one oxidoreductase, NADPH-dependent alkenal/one oxidoreductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.74 2-alkenal reductase [NAD(P)+]

KM Value

KM Value on EC 1.3.1.74 - 2-alkenal reductase [NAD(P)+]

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.465
(+)-acylfulvene
-
pH 7.2, 37C
0.243
(+)-hydroxymethylacylfulvene
-
pH 7.2, 37C
0.538
(-)-acylfulvene
-
pH 7.2, 37C
0.213
(-)-hydroxymethylacylfulvene
-
pH 7.2, 37C
0.232
(2E)-hexenal
-
pH 6
0.005
(2E)-nonenal
-
pH 6
1.42
(2E)-pentenal
-
pH 6
0.0113
(2E,6Z)-nonadienal
-
pH 6.0
0.29 - 0.58
1-penten-3-one
0.00392
13-oxo-(9E,11Z)-octadecadienoic acid
-
pH 6.0
0.0096
15-deoxy-DELTA12,14-prostaglandin J2
-
pH 7.2
0.001
15-oxoprostaglandin E1
-
30C
0.02
2-[4-[(E)-(2-oxocyclohexylidene)methyl]phenyl]propanoic acid
-
at 30C
0.0064
2E-nonenal
-
pH 7.0, 30C
0.055 - 2.88
3-buten-2-one
0.000673
3-nonen-2-one
-
pH 6.0
0.0052 - 0.63
3-penten-2-one
0.023 - 0.12
4-hexen-3-one
0.145
4-hydroxy-(2E)-hexenal
-
pH 6
0.0134
4-hydroxy-(2E)-nonenal
0.12
4-hydroxy-2-nonenal
-
30C
0.00124
4-oxo-(2E)-nonenal
-
pH 6.0
0.01
9-oxo-(10E,12Z)-octadecadienoic acid
-
pH 6.0
0.15
acrolein
-
30C
0.071
artemisinic aldehyde
-
pH 7.0, 30C
1.8 - 29.8
crotonaldehyde
0.128
Diamide
-
pH 6
0.11
ethyl vinyl ketone
-
30C
0.109
illudin M
-
recombinant enzyme, pH 7.4, 37C
0.308
illudin S
-
recombinant enzyme, pH 7.4, 37C
0.145
irofulven
-
recombinant enzyme, pH 7.4, 37C
0.053 - 4.64
NADH
0.004 - 0.185
NADPH
3.5 - 13.6
propenal
0.078
trans-2-nonenal
-
recombinant enzyme, pH 7.2, 25C
0.24
trans-2-pentenal
-
pH 7.2
0.028
trans-3-nonen-2-one
-
recombinant enzyme, pH 7.2, 25C
additional information
additional information
-
ordered Theorell-Chance kinetic mechanism, steady-state kinetics, detailed analysis, kinetic isotopic effects
-