1.3.1.74: 2-alkenal reductase [NAD(P)+]

This is an abbreviated version!
For detailed information about 2-alkenal reductase [NAD(P)+], go to the full flat file.

Word Map on EC 1.3.1.74

Reaction

a n-alkanal
+
NAD(P)+
=
an alk-2-enal
+
NAD(P)H
+
H+

Synonyms

2-alkenal reductase, 2AER, AER, alkenal/one oxidoreductase, alkenal/one reductase, AOR, At-AER, At5g16970, AtAOR, bifunctional LTB4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase, CS-670 double-bond reductase, CsAOR, Dbr1, double bond reductase, LTB4 12-HD/PGR, NADPH alkenal/one oxidoreductase, NADPH-dependent alkenal/one oxidoreductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.74 2-alkenal reductase [NAD(P)+]

Inhibitors

Inhibitors on EC 1.3.1.74 - 2-alkenal reductase [NAD(P)+]

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
15-keto prostaglandin F2alpha
-
43.06% residual activity at 0.1 mM
2-nonanone
-
product inhibition, competitive versus trans-3-nonen-2-one
benzylidene acetophenone
-
21.09% residual activity at 0.5 mM
cyclovalone
-
-
dicoumarol
-
11.45% residual activity at 0.1 mM
illudin M
-
-
illudin S
-
-
indomethacin
-
14.22% residual activity at 0.1 mM
irofulven
-
recombinant human 293 cells show 100fold increased sensitivity compared to the wild-type human 293 cells
NADP+
-
product inhibition, competitive versus NADPH
progesterone
-
-
quercetin
-
-
quercitrin
-
13.14% residual activity at 0.1 mM
additional information
-