1.3.1.54: precorrin-6A reductase

This is an abbreviated version!
For detailed information about precorrin-6A reductase, go to the full flat file.

Reaction

precorrin-6B
+
NADP+
=
precorrin-6A
+
NADPH
+
H+

Synonyms

precorrin 6-X reductase, precorrin-6 reductase, precorrin-6A reductase, precorrin-6x reductase, precorrin-6Y:NADP+ oxidoreductase, Reductase, precorrin 6x (Pseudomonas denitrificans clone pXL367 gene cobK)

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.54 precorrin-6A reductase

Reference

Reference on EC 1.3.1.54 - precorrin-6A reductase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Roessner, C.A.; Spencer, J.B.; Ozaki, S.; Min, C.; Atshaves, B.P.; Nayar, P.; Anousis, N.; Stolowich, N.J.; Holderman, M.T.; Scott, A.I.
Overexpression in Escherichia coli of 12 vitamin B12 biosynthetic enzymes
Protein Expr. Purif.
6
155-163
1995
Pseudomonas denitrificans (nomen rejiciendum)
Manually annotated by BRENDA team
Blanche, F.; Thibaut, D.; Famechon, A.; Debussche, L.; Cameron, B.; Crouzet, J.
Precorrin-6x reductase from Pseudomonas denitrificans: purification and characterization of the enzyme and identification of the structural gene
J. Bacteriol.
174
1036-1042
1992
Pseudomonas denitrificans (nomen rejiciendum)
Manually annotated by BRENDA team
Shearer, N.; Hinsley, A.P.; Van Spanning, R.J.; Spiro, S.
Anaerobic growth of Paracoccus denitrificans requires cobalamin: characterization of cobK and cobJ genes
J. Bacteriol.
181
6907-6913
1999
Paracoccus denitrificans (Q9R9K2), Paracoccus denitrificans, Paracoccus denitrificans Pd 1222 (Q9R9K2)
Manually annotated by BRENDA team
Kiuchi, F.; Thibaut, D.; Debussche, L.; Leeper, F.; Blanche, F.; Battersby, A.R.
Biosynthesis of vitamin B12: stereochemistry of transfer of a hydride equivalent from NADPH by precorrin-6x reductase
J. Chem. Soc.
Chem. Commun.
306-308
1992
Pseudomonas denitrificans (nomen rejiciendum), Pseudomonas denitrificans (nomen rejiciendum) SC510 Rif
-
Manually annotated by BRENDA team
Kim, W.; Major, T.A.; Whitman, W.B.
Role of the precorrin 6-X reductase gene in cobamide biosynthesis in Methanococcus maripaludis
Archaea
1
375-384
2005
Methanococcus maripaludis (Q977V1), Methanococcus maripaludis, Methanococcus maripaludis JJ (Q977V1)
Manually annotated by BRENDA team