1.3.1.48: 13,14-dehydro-15-oxoprostaglandin 13-reductase

This is an abbreviated version!
For detailed information about 13,14-dehydro-15-oxoprostaglandin 13-reductase, go to the full flat file.

Word Map on EC 1.3.1.48

Reaction

11alpha-hydroxy-9,15-dioxoprostanoate
+
NAD(P)+
=
(13E)-11alpha-hydroxy-9,15-dioxoprost-13-enoate
+
NAD(P)H
+
H+

Synonyms

15-hydroxyprostaglandin dehydrogenase, 15-keto-PG reductase, 15-ketoprostaglandin DELTA-13-reductase, 15-ketoprostaglandin DELTA13-reductase, 15-ketoprostaglandinDELTA13-reductase, 15-oxoprostaglandin 13-oxidase, 15-oxoprostaglandin 13-reductase, 15-oxoprostaglandin DELTA13-reductase, 15-oxoprostaglandin-DELTA13-reductase, 15-PGDH, Ad-PGR, bifunctional leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase, bifunctional LTB4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase, DELTA13-15-ketoprostaglandin reductase, leukotriene B4 12-hydroxydehydrogenase/15-ketoprostaglandin 13-reductase, leukotriene B4 dehydrogenase, leukotriene B4-12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase, LTB4 12-HD/PGR, LTBDH/PGR, NAD(P)H-dependent alkenal/one oxidoreductase, PG reductase, PGR, PGR-2, PGR1, prostaglandin 13-reductase, prostaglandin DELTA13-reductase, prostaglandin reductase 1, reductase, 15-oxo-DELTA13-prostaglandin

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase

Substrates Products

Substrates Products on EC 1.3.1.48 - 13,14-dehydro-15-oxoprostaglandin 13-reductase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(13E)-11alpha-hydroxy-9,15-dioxoprost-13-enoate + NADPH + H+
11alpha-hydroxy-9,15-dioxoprostanoate + NADP+
show the reaction diagram
-
-
-
?
(5S,12R)-dihydroxy-(6E,8Z,10Z,14E)-eicosatetraenoic acid + NADH
?
show the reaction diagram
(5S,6R)-dihydroxy-15-oxo-(7E,9E,11Z,13E)-eicosatetraenoic acid + NADH
13,14-dihydro-(5S,6R)-dihydroxy-15-oxo-(7E,9E,11Z)-eicosatetraenoic acid + NAD+
show the reaction diagram
-
trivial name 15-oxo-lipoxin A4
-
?
(5Z,13E)-11alpha-hydroxy-9,15-dioxoprost-5,13-dienoate + NAD(P)H
(5Z)-11alpha-hydroxy-9,15-dioxoprost-5-enoate + NAD(P)+
show the reaction diagram
(Z)-3-[(5-methoxy-3-oxo-2(3H)-benzofuranylidene)-methyl]benzoic acid + NAD(P)H
3-[(5-methoxy-3-oxo-2,3-dihydro-1-benzofuran-2-yl)methyl]benzoic acid + NAD(P)+
show the reaction diagram
-
-
-
?
1-(p-carboxyphenyl)-5-cyano-3-oxo-1-pentene + NAD(P)H
1-(p-carboxyphenyl)-5-cyano-3-oxo-pentane + NAD(P)+
show the reaction diagram
-
-
-
?
11-hydroxy-9,15-dioxoprosta-5,13-dien-1-oic acid + NAD(P)H
11-hydroxy-9,15-dioxoprosta-5-en-1-oic acid + NAD(P)+
show the reaction diagram
11-hydroxy-9,15-dioxoprosta-5,13-dien-1-oic acid + NADPH
11-hydroxy-9,15-dioxoprosta-5-en-1-oic acid + NADP+
show the reaction diagram
-
-
-
-
?
11alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+
(13E)-11alpha-hydroxy-9,15-dioxoprost-13-enoate + NAD(P)H + H+
show the reaction diagram
-
-
-
?
15-ketoprostaglandin A1 + NAD(P)H
?
show the reaction diagram
15-ketoprostaglandin B1 + NAD(P)H
?
show the reaction diagram
15-ketoprostaglandin E + NAD(P)H
?
show the reaction diagram
15-ketoprostaglandin E1 + NADPH
?
show the reaction diagram
15-ketoprostaglandin E2 + NADPH
13,14-dihydro-15-keto-prostaglandin E2 + NADP+
show the reaction diagram
-
-
-
?
15-ketoprostaglandin E2 + NADPH
?
show the reaction diagram
-
-
-
-
?
15-ketoprostaglandin F1alpha + NAD(P)H
?
show the reaction diagram
15-ketoprostaglandin F1alpha + NADPH
?
show the reaction diagram
-
-
-
?
15-ketoprostaglandin F2alpha + NADPH
?
show the reaction diagram
15-oxoprostaglandin F1alpha + NAD(P)H
?
show the reaction diagram
3-nonen-2-one + NADPH
nonane-2-one + NADP+
show the reaction diagram
-
-
-
?
3-penten-2-one + NADPH
pentane-2-one + NADP+
show the reaction diagram
-
-
-
?
4-hydroxy-2-hexenal + NADPH
4-hydroxyhexanal + NADP+
show the reaction diagram
-
-
-
?
4-hydroxy-2-nonenal + NADPH
4-hydroxynonanal + NADP+
show the reaction diagram
-
-
-
?
4-hydroxy-2-nonenal + NADPH
?
show the reaction diagram
-
-
-
-
?
6,15-diketo-prostaglandin F1alpha + NAD(P)H
?
show the reaction diagram
-
-
-
-
?
9,11-dihydroxy-15-oxoprosta-5,13-dien-1-oic acid + NAD(P)H
9,11-dihydroxy-15-oxoprosta-5-en-1-oic aicd + NAD(P)+
show the reaction diagram
acrolein + NADPH
propanal + NADP+
show the reaction diagram
-
-
-
?
alpha-methylcinnamaldehyde + NADPH
?
show the reaction diagram
-
-
-
-
?
benzylidene acetone + NADPH
?
show the reaction diagram
-
-
-
-
?
benzylidene acetonphenone + NADPH
?
show the reaction diagram
-
-
-
-
?
beta-ionone + NAD(P)H
?
show the reaction diagram
-
-
-
-
?
chalcone + NADPH
?
show the reaction diagram
-
-
-
-
?
cinnamaldehyde + NADPH
?
show the reaction diagram
-
-
-
-
?
cinnamoylthiophene + NADPH
?
show the reaction diagram
-
-
-
-
?
curcumin + NAD(P)H
?
show the reaction diagram
-
-
-
-
?
ethylvinylketone + NADPH
pentane-3-one + NADP+
show the reaction diagram
-
-
-
?
leukotriene B4 + NADPH
?
show the reaction diagram
methyl vinyl ketone + NADPH
?
show the reaction diagram
-
-
-
-
?
phenyl propenyl ketone + NADPH
?
show the reaction diagram
-
-
-
-
?
prostaglandin E2 + NADP+
15-ketoprostaglandin E2 + NADPH + H+
show the reaction diagram
-
-
-
-
?
trans-2-(o-hydroxybenzylidene)acetophenone + NAD(P)H
(o-hydroxybenzyl)acetophenone + NAD(P)+
show the reaction diagram
-
-
-
?
trans-2-benzylidenecyclohexan-2-one + NAD(P)H
benzylcyclohexan-2-one + NAD(P)+
show the reaction diagram
-
-
-
?
trans-2-butenal + NAD(P)H
butanal + NAD(P)+
show the reaction diagram
trans-2-decenal + NADPH
decanal + NADP+
show the reaction diagram
-
-
-
?
trans-2-decenal + NADPH + H+
decanal + NADP+
show the reaction diagram
-
-
-
?
trans-2-dodecenal + NADPH
dodecanal + NADP+
show the reaction diagram
-
-
-
?
trans-2-hexenal + NAD(P)H
hexanal + NAD(P)+
show the reaction diagram
trans-2-hexenal + NADPH
?
show the reaction diagram
-
-
-
-
?
trans-2-nonenal + NADPH
nonanal + NADP+
show the reaction diagram
-
-
-
?
trans-2-octenal + NADPH
octanal + NADP+
show the reaction diagram
-
-
-
?
trans-2-pentenal + NADPH
pentanal + NADP+
show the reaction diagram
-
-
-
?
trans-3-(2-furyl)acrolein + NAD(P)H
2-furylpropanal + NAD(P)+
show the reaction diagram
-
-
-
?
trans-3-nonen-2-one + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
?
trans-4-furyl-3-buten-2-one + NAD(P)H
4-furyl-butane-2-one + NAD(P)+
show the reaction diagram
-
-
-
?
trans-benzylideneacetone + NAD(P)H
benzylacetone + NAD(P)+
show the reaction diagram
trans-benzylideneacetophenone + NAD(P)H
benzylacetophenone + NAD(P)+
show the reaction diagram
-
-
-
?
trans-cinnamaldehyde + NAD(P)H
?
show the reaction diagram
trans-cinnamic acid ethyl ester + NAD(P)H
?
show the reaction diagram
-
-
-
-
?
trans-cinnamoyl thiophene + NAD(P)H
?
show the reaction diagram
-
-
-
-
?
trans-methylvinylketone + NAD(P)H
butane-2-one + NAD(P)+
show the reaction diagram
trans-phenyl-1-propenyl ketone + NAD(P)H
phenylpropane-1-one + NAD+
show the reaction diagram
-
-
-
?
trans-trans-2,4-hexadienal + NAD(P)H
?
show the reaction diagram
additional information
?
-