1.3.1.45: 2'-hydroxyisoflavone reductase

This is an abbreviated version!
For detailed information about 2'-hydroxyisoflavone reductase, go to the full flat file.

Word Map on EC 1.3.1.45

Reaction

vestitone
+
NADP+
=
2'-hydroxyformononetin
+
NADPH
+
H+

Synonyms

CaIRL, GbIRL1, GmIFR, IFR, IRL, isoflavone reductase, isoflavone reductase-like protein, LOC100786578, More, NADPH:2'-hydroxyisoflavone oxidoreductase, Ole e 12, OsIRL, PvIFR1, reductase, 2',7-dihydroxy-4',5'-methylenedioxyisoflavone, reductase, 2'-hydroxyisoflavone

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.45 2'-hydroxyisoflavone reductase

Reference

Reference on EC 1.3.1.45 - 2'-hydroxyisoflavone reductase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Tiemann, K.; Hinderer, W.; Barz, W.
Isolation of NADPH:isoflavone oxidoreductase, a new enzyme of pterocarpan phtoalexin biosynthesi in cell suspension cultures of Cicer arietinum
FEBS Lett.
213
324-328
1987
Cicer arietinum
-
Manually annotated by BRENDA team
Schlieper, D.; Tiemann, K.; Barz, W.
Stereospecificity of hydrogen transfer by fungal and plant NADPH:isoflavone oxidoreductases
Phytochemistry
29
1519-1524
1990
Cicer arietinum
-
Manually annotated by BRENDA team
Preisig, C.L.; Bell, J.N.; Sun, Y.; Hrazdina, G.; Matthews, D.E.; VanEtten, H.D.
Biosynthesis of the phytoalexin pisatin. Isoflavone reduction and further metabolism of the product sophorol by extracts of Pisum sativum
Plant Physiol.
94
1444-1448
1990
Pisum sativum
Manually annotated by BRENDA team
Paiva, N.L.; Sun, Y.; Dixon, R.A.; VanEtten, H.D.; Hrazdina, G.
Molecular cloning of isoflavone reductase from pea (Pisum sativum L.): evidence for a 3R-isoflavanone intermediate in (+)-pisatin biosynthesis
Arch. Biochem. Biophys.
312
501-510
1994
Pisum sativum
Manually annotated by BRENDA team
Cooper, J.D.; Qiu, F.; Paiva, N.L.
Biotransformation of an exogenously supplied isoflavonoid by transgenic tobacco cells expressing alfalfa isoflavone reductase
Plant Cell Rep.
20
876-884
2002
Medicago sativa
-
Manually annotated by BRENDA team
Saunders, J.; O'Neill, N.
The characterization of defense responses to fungal infection in alfalfa
BioControl
49
715-728
2004
Medicago sativa
-
Manually annotated by BRENDA team
Lopez-Meyer, M.; Paiva, N.L.
Immunolocalization of vestitone reductase and isoflavone reductase, two enzymes involved in the biosynthesis of the phytoalexin medicarpin
Physiol. Mol. Plant Pathol.
61
15-30
2002
Medicago sativa
Manually annotated by BRENDA team
Wang, X.; He, X.; Lin, J.; Shao, H.; Chang, Z.; Dixon, R.A.
Crystal structure of isoflavone reductase from alfalfa (Medicago sativa L.)
J. Mol. Biol.
358
1341-1352
2006
Medicago sativa
Manually annotated by BRENDA team
Kim, S.G.; Kim, S.T.; Wang, Y.; Kim, S.K.; Lee, C.H.; Kim, K.K.; Kim, J.K.; Lee, S.Y.; Kang, K.Y.
Overexpression of rice isoflavone reductase-like gene (OsIRL) confers tolerance to reactive oxygen species
Physiol. Plant.
138
1-9
2009
Oryza sativa, Oryza sativa (Q8VYH7)
Manually annotated by BRENDA team
Brandalise, M.; Severino, F.E.; Maluf, M.P.; Maia, I.G.
The promoter of a gene encoding an isoflavone reductase-like protein in coffee (Coffea arabica) drives a stress-responsive expression in leaves
Plant Cell Rep.
28
1699-1708
2009
Coffea arabica (C7BFZ4)
Manually annotated by BRENDA team
Zhu, Q.L.; Guo, T.Y.; Sui, S.Z.; Liu, G.D.; Lei, X.H.; Luo, L.L.; Li, M.Y.
Molecular cloning and characterization of a novel isoflavone reductase-like gene (FcIRL) from high flavonoids-producing callus of Fagopyrum cymosum
Yao Xue Xue Bao
44
809-819
2009
Fagopyrum cymosum (A7Y232)
Manually annotated by BRENDA team
Hua, C.; Linling, L.; Feng, X.; Yan, W.; Honghui, Y.; Conghua, W.; Shaobing, W.; Zhiqin, L.; Juan, H.; Yuping, W.; Shuiyuan, C.; Fuliang, C.
Expression patterns of an isoflavone reductase-like gene and its possible roles in secondary metabolism in Ginkgo biloba
Plant Cell Rep.
32
637-650
2013
Ginkgo biloba, Ginkgo biloba (M1T9X3)
Manually annotated by BRENDA team
Castro, L.; Crespo, J.F.; Rodriguez, J.; Rodriguez, R.; Villalba, M.
Immunoproteomic tools are used to identify masked allergens Ole e 12, an allergenic isoflavone reductase from olive (Olea europaea) pollen
Biochim. Biophys. Acta
1854
1871-1880
2015
Olea europaea
Manually annotated by BRENDA team
Cheng, Q.; Li, N.; Dong, L.; Zhang, D.; Fan, S.; Jiang, L.; Wang, X.; Xu, P.; Zhang, S.
Overexpression of soybean isoflavone reductase (GmIFR) enhances resistance to phytophthora sojae in soybean
Front. Plant Sci.
6
1024
2015
Glycine max (C6TER4), Glycine max
Manually annotated by BRENDA team
Qian, X.; Xu, S.; Zhao, C.; Meng, H.; Wen, G.
cDNA cloning and expression analyses of the isoflavone reductase-like gene of Dendrobium officinale
Pak. J. Bot.
47
1265-1270
2015
Dendrobium catenatum (A0A068ERY8)
-
Manually annotated by BRENDA team
Ripodas, C.; Via, V.D.; Aguilar, O.M.; Zanetti, M.E.; Blanco, F.A.
Knock-down of a member of the isoflavone reductase gene family impairs plant growth and nodulation in Phaseolus vulgaris
Plant Physiol. Biochem.
68
81-89
2013
Phaseolus vulgaris
Manually annotated by BRENDA team